The billionaires funding aging reversal. When they were young they wanted to be rich. When they were rich, they wanted to be young. shane shifflett Amy Dockser Marcus Alex Janin wsj.com/health/wellnes…

NEW content online! Unravelling the genetics and epigenetics of the ageing tumour microenvironment in cancer bit.ly/46tAJqg

A blood-based DNA damage signature predicts Parkinson’s progression. In >480 patients (PPMI cohort), defective DNA repair + long-gene transcription bias were found only in those with faster motor decline. #Parkinsons #Biomarkers nature.com/articles/s4358…

Multi-ancestry brain #proteomics study finds 119 variant–protein pairs likely causing 21 neurological disorders, nature.com/articles/s4158…

Alzheimer’s Biomarkers: Large #proteomic study (~2,600 plasma samples) links multiple blood proteins to #Alzheimer’s pathology beyond amyloid & tau. nature.com/articles/s4358…

Global, regional, and national cascades of diabetes care, 2000–23: a systematic review and modelling analysis using findings from the Global Burden of Disease Study thelancet.com/journals/landi… #diabetes

The emerging "nudge era" of cancer treatment based on multiomic profiling, spatial biology cell.com/cancer-cell/ab…

Nature research paper: Functional synapses between neurons and small cell lung cancer go.nature.com/41Ne5qi

A Risk Prediction Tool for Invasive Melanoma jamanetwork.com/journals/jamad…

Exact Sciences enters early-detection market statnews.com/2025/09/11/exa… via STAT

Viewpoint: Oncology is shifting toward personalized, less aggressive treatments for "good-risk" metastatic prostate cancer and similar tumors, prioritizing efficacy and quality of life over overtreatment. ja.ma/3VcVYGz

Partitioning obesity by genomics, proteomics and health outcomes from >450,000 UK Biobank participants Nature Medicine —A protective subtype vs cardiometabolic diseases (GRS BFP) and —A risk subtype for these diseases (GRS uncoupling) GRS-genomic risk score

Without reliable measures of biological age, translating longevity research to patients is hindered. #Longevity #Biomarkers nature.com/articles/s4158…

High-throughput proteomics is entering a new era. science.org/doi/10.1126/sc…

We know GLP-1 drugs reduce brain inflammation. But I didn't anticipate bipolar disorder as a possible indication in the future nature.com/articles/s4138…

p-tau 217 as a stand-alone blood marker establishes risk of Alzheimer's disease in cognitively unimpaired individuals (again) jamanetwork.com/journals/jaman…

The cohort study identifies two trajectories of suicidal ideation: early adolescence onset linked to childhood mental health issues, and young adulthood onset related to adolescent internalizing symptoms. ja.ma/3JKdAXQ

The global, regional, and national burden of cancer, 1990–2023, with forecasts to 2050: a systematic analysis for the Global Burden of Disease Study 2023 - The Lancet thelancet.com/journals/lance…