AORTIC Dr. Hannah Ayettey Anie (Q2) With regards you cancer treatment and clinical research, in what ways can genomics sharpen cancer research and clinical care in Africa? #AfricancancerGenomics Solomon Rotimi Prof FTO 🇳🇬🇺🇸

Ruth Agaba(✸,✸)🔆 AORTIC Solomon Rotimi Prof FTO 🇳🇬🇺🇸 Development of a research agenda for Africa and eventually the African cancer genome will go a long way to tailor treatment to the needs of the African cancer patient. #AfricanCancerGenomics #AfricanCancer

It's with the permission of African elders like you, ma. If it's #African, it must come with #proverbs and adages. Proverbs are the chariots that words ride on. (with permission)😂😂😂😂 It's all in the spirit of #AfricanCancerGenomics

Solomon Rotimi We are gearing up for more at the conference 🤣🤣

Pedro W. Fernandez, PhD AORTIC #AfricanCancerGenomics

Omolara Fatiregun AORTIC Solomon Rotimi The sad reality is that most genomics studies, particularly GWAS, have focused almost exclusively on populations of European ancestry, with less than 4% having included populations of African ancestry.

Omolara Fatiregun AORTIC Solomon Rotimi This article sums up the reality, I recommend you read it if you have an interest in prostate cancer or other cancers as well: pubmed.ncbi.nlm.nih.gov/33302594/

Omolara Fatiregun AORTIC Solomon Rotimi However, African populations have much to offer, the linkage disequilibrium blocks in African populations are significantly smaller than European populations, thus allowing fine mapping to pin-point causal variants, or variants that increase disease risk.

AORTIC I introduce you to our next speaker amaka lasebikan Please Dr. Amaka Lasebikan introduce yourself AORTIC #AfricancancerGenomics

Omolara Fatiregun AORTIC Solomon Rotimi African populations also have unique variant that are rare in other populations, these variants may have modifier effects that influence tumour pathology or response to treatment.

Ruth Agaba(✸,✸)🔆 AORTIC Hello Ruth Agaba(✸,✸)🔆. Privileged to be part of this discussion #africancancergenomics

AORTIC amaka lasebikan Implementation Science and Cancer Genomics in Africa, Is there a link? can we explore this link to reduce the cancer burden in Africa? #AfricancancerGenomics AORTIC

Ruth Agaba(✸,✸)🔆 AORTIC I am Amaka Lasebikan, a clinical oncologist at the University of Nigeria teaching hospital Enugu Nigeria. I am a member of the AORTIC Research committee and the Chair of the African Research and control ECHO.

Ruth Agaba(✸,✸)🔆 AORTIC My interests are in cancer prevention, genomic epidemiology and implementation science. My clinical interests are in breast and GI malignancies and both are heavily influenced by genomics

Pedro W. Fernandez, PhD AORTIC Solomon Rotimi Thanks so much Dr Pedro, your comments have shed some light on your further discussions at the genomics conference. #AfricanCancerGenomics

AORTIC We really appreciate all our speakers today. The final question for this twitter chat goes to Belmira AORTIC What are the benefits of joining AORTIC. AORTIC Solomon Rotimi #AfricanCancerGenomics

Thank you Omolara Fatiregun Free access to Cancer Genomics Conference! Reduced fees AORTIC 2021 coming up - 7-10 Nov 2021! Eligible to apply for bursaries, join committees & much, much, more! See full benefits & join here! 👇 aortic-africa.org/become-a-membe… #AfricanCancerGenomics

AORTIC Thanks again to all our speakers and attendees, expect indepth discussions at the Genomics conference (February 18-19th 2020) !!!!! AORTIC Solomon Rotimi Dr. Hannah Ayettey Anie Prof FTO 🇳🇬🇺🇸 amaka lasebikan

Great session! Thanks Omolara Fatiregun and Ruth Agaba(✸,✸)🔆 for outstanding moderation!

NEW Comment! F.T. Odedina Prof FTO 🇳🇬🇺🇸 & S. Rotimi Solomon Rotimi discuss how we can promote #CancerGenomics research in Africa to help us understand the genetic architecture of cancer and tailor diagnoses and therapies to African populations. go.nature.com/3seR62G