Amazing visualizations from Rommie Amaro's lab! Got see her present these images at a recent #TeamAPOBEC meeting. Their modeling of the glycan shield and discovery of a potential structural role was particularly fascinating. Check out their pub in ACS Central Science if you get a chance.

Exciting news this Saturday morning: a third paper from my post-bac research position was published in FSI: Genetics! Does differential hair growth across the scalp affect protein polymorphism profiles within an individual? Check it out! authors.elsevier.com/c/1bwR5_garvmm…

The president-elect's #covid19 task force is stacked with some of the best healthcare minds in America, including Atul Gawande Michael Osterholm Rick Bright Zeke Emanuel Céline Gounder, MD, ScM, FIDSA 🇺🇦 Vivek Murthy statnews.com/2020/11/09/bid…

There's more good news today, #Covid19 vaccines-wise, than might immediately meet the eye from the Pfizer preliminary analysis. Let's unpack. statnews.com/2020/11/09/fou…

A great paper to work on, in which we developed a new type of ALARM assay using mass spec peptide sequencing to identify binding of reversible covalent compounds! Check it out!

Thanks, Dan! A big shout out goes to our whole lab, who helped me prepare and gave me awesome feedback for the presentation! Jian Tang Kellan Tri Phosphate Samantha Kennelly Anand Divakaran

The 2021 version of the #HarkiLab! Not pictured: Deborah Rodriguez and Anand Divakaran. University of Minnesota Medicinal Chemistry UMN Department of Chemistry Masonic Cancer Center, University of Minnesota

Small Molecule of the Year, 2020: drughunter.com/2020smotygs/ The drug discovery community voted on their favorite molecule from 2020, and their 2020 pick is GS-6207, Gilead Sciences awe-inspiring HIV capsid inhibitor. Full story at drughunter.com. #chemtwitter #biotwitter

Lab Dan is ready for the best time of the year — baseball season! Dan Harki

Also a reminder for any grad student being paid by a not pre-taxed fellowship like the NSF GRFP!

A COVID Saturday night means board games feat Polyoply, the polymer version of Monopoly feat UMN Department of Chemistry professors

The 2022 version of the #HarkiLab! University of Minnesota Medicinal Chemistry UMN Department of Chemistry Masonic Cancer Center, University of Minnesota

Our review (Dan Harki @HarrisLabUMN) on the current toolbox for APOBEC3 drug discovery is online now at Trends in Pharmacological Sciences! So happy to see my first review paper finally out in the world! cell.com/trends/pharmac…

Exciting new research from Jian Tang that I was happy to be a part of is finally out in the world! Folks at #AACR22, go to his talk this afternoon!

If you’re looking for a postdoc position in medicinal chemistry or chemical biology, come join our lab! #chempostdoc

Honored to have received this fellowship alongside these other amazing chemists!

If you’re at #ACSFall2022 and you love drug discovery, come see me present my poster on our virtual and in vitro screening project for APOBEC3B inhibitors!

Very excited to have this paper from my time in grad school published! Started from an unrelated project idea that lead to weird results. Working on #APOBEC3A? Your catalytic inactivation mutation may lead to unstable protein! Check out the paper below to learn why E72A > E72Q.