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DICTATE-AHF trial shows early initiation of SGLT2i dapagliflozin within 24hr of acute HF presentation does not improve diuretic efficiency, but length of stay significantly reduced with dapagliflozin. Dr. Cox and I discuss results of DICTATE-AHF #ESCCongress

DICTATE-AHF & PUSH-AF trials presented at #ESCCongress shed light on treatments for acute #HeartFailure; trials assess safety/efficacy of dapagliflozin w/in 24-hour of hospitalization & use of a natriuresis-guided diuretic approach to managing pts. bit.ly/45nbCTc

Read our #PUSHAHF trial here in Nature Medicine !!! nature.com/articles/s4159…

DICTATE-AHF top line results were presented at #ESCCongress2023 KEY MESSAGE: Dapagliflozin is safe to start on the first day of AHF hospitalization to optimize #gdmt Addironally, diuretic benefits have meaningful impact on AHF discharge rates over the study period

What timing! The full paper of our evaluation of the PHARM-HF clinic is now live JACCP accpjournals.onlinelibrary.wiley.com/doi/epdf/10.10…

Happy #WorldDownSyndromeDay My son Cooper brightens our day. Hope you have a friend with Down Syndrome in your life to enrich your days too.

Despite #dapagliflozin not improving diuretic efficiency in the setting of acute HF hospitalization, it was associated with fewer diuretic doses to achieve the same weight change as usual care American College of Cardiology Zachary Cox #Cardiotwitter Lipscomb College of Pharmacy Read more👇 healio.com/news/cardiolog…

In #DICTATE trial, dapagliflozin was safe to start first day of AHF hospitalization before stabilization to optimize #GDMT & improve some measures of diuresis. #SGLT2i should be started immediately or continued in most pts hospitalized for AHF bit.ly/3VK4fmK #JACC Zachary Cox

Greetings All. As many of you have likely seen, I am on the ballot this year to become a Regent of ACCP. The voting closes this Friday before Midnight Central time. I humbly ask for your support and vote. ACCP Cardiology PRN ACCP Txp PRN UConn Pharmacy

Check out our review on "SGLT2i and GU infections" in JACC Journals 🔗: shorturl.at/gsGL7 Here we discuss - SGLT2i mechanisms/benefits - Trial/real-world evidence of SGLT2i/GU ifx - Risk factors - Practice considerations 🧵 to follow (1/5)

Join us at kick off sessions #HFSA2024 on Heart Recovery: Just the Facts, Ma'am! Looking forward to share thoughts on temporary #MCS & insightful discussions with thought leaders! 📆 9/27/24 🕰️ 500 pm EST Joseph Rogers Jerry Estep Zachary Cox Filio Billia Eman R. Rashed, MD, PhD Nosheen Reza, MD, MS

Costs? Intolerance? Inertia? Other? Primary reason for gaps in #GDMTworks endlessly debated. 🤔What if we had US physicians audit their own patient charts & report *WHY* they didn’t prescribe #GDMT for #HFrEF in each case? 🚨 Results in JACC Journals jacc.org/doi/epdf/10.10…

A 🕵🏽‍♀️ theme for our session on myocardial recovery vs. remission — drugs, devices, and the interplay of them all with Varinder Kaur Randhawa Filio Billia Zachary Cox Anju Bhardwaj MD FACC Dr. Joe Rogers and Dr. Jerry Estep #HFSA2024 HFSA

🔥 New brief report describes a first-in-human feasibility study to evaluate the safety/efficacy of the Reprieve System, a bedside fluid mgmnt device that can 1) measure UO 2) semi-auto titrate IV diuretics 3) titrate saline replacement #THT2025 🔗 bit.ly/4huGrvq

At #THT2025, experts dive into the complex role of salt in #HeartFailure 🧂, from molecular mechanisms 🧬 to clinical trials 📊 and real-world management 🏥. Don’t miss the latest insights, crucial data, and a debate on salt restriction! ⚖️💡 Maria Rosa Costanzo Jan Biegus @zac0x

Our review on drugs and devices for decongestion in #heartfailure is available Nature Reviews Cardiology x.com/NatRevCardiol/… Lipscomb College of Pharmacy Yale Heart Failure Kevin Damman