I am looking for a Postdoctoral Researcher to work on different Neuroimaging projects in at Karolinska Institute, the home for the Nobel Prize in Medicine. For more information about the position and how to apply please go to: ki.varbi.com/en/what:job/jo… The deadline is 29/04/2022.

Preprint! Liisa Raud tested hippo-cortex FC n=751 w rest + two memory tasks: retrieval shows a specific pattern indicative of a task-general process; encoding reflects context-specific demands, not a task-general cognitive construct - quite cool LCBC - UiO biorxiv.org/content/10.110…

What influences how your brain looks in aging? Prenatal factors (i.e. birth weight) have large, stable and consistent effects. Supporting early effects on brain reserve through life, even in MZ twins. >12k MRIs from 5.8k participants. Kristine B Walhovd LCBC - UiO biorxiv.org/content/10.110…

Finally (!) out in eLife - the journal 📢 We use replicable effects in adults to trace two forms of brain development never before tracked across life and time: one grows through childhood and adolescence and peaks in the mid-20s (cortical thickness asymmetry) bit.ly/3qYowYn

Much of the differences between people in aging are caused by early - even prenatal - factors. These are at least partly environmental: birth weight differences in MZ twins correlate with late-life brain structure. Check out eLife - the journal Kristine B Walhovd Didac Vidal Pineiro elifesciences.org/reviewed-prepr…

Remarkably similar effects of fetal influences across development, mid-life and aging, at least in part no-genetic. Thanks for posting @parkvillegeek ! Kristine B Walhovd Didac Vidal Pineiro LCBC - UiO

Preprint: we study SuperAgers - less hippo atrophy and more retrieval-related activity associated with superior memory across adult life, not only in aging. Hence, hippo correlates of superior memory are stable, not specific to aging. LCBC - UiO Kristine B Walhovd biorxiv.org/content/10.110…

Check our latest work where we assess the reliability of longitudinal MRI based data and the effect of follow-up time, number of observations, sample characteristics, and preprocessing pipeline biorxiv.org/content/10.110…

Kicking off my new job by (almost) finalizing one of my previous projects 😄. Another major result from our #BBSC_project: Title: The within-subject stability of cortical thickness, surface area, and brain volumes across one year biorxiv.org/content/10.110… 👇

Really interesting from Didac Vidal Pineiro Follow-up time much more important for reliability than number of timepoints; extend from 2 to 4 yrs yields MUCH larger improvements than adding 6 (!) more TPs. Comes with a shiny app to explore reliability, sample size and power👏 LCBC - UiO

We find higher brain activity 12h after learning for memories still intact 6 days later. Despite perfect memory for all items at 6h, activity distinguishes long-term durable from transient memories. LCBC - UiO

Preprint on brain aging. From single timepoint data, estimate if delta reflects subject-varying aging rates vs baseline variations. For common analyses, baseline effects tend to dominate, whereas multiple aging modes show a range of results. biorxiv.org/content/10.110…

Preprint from Didac Vidal Pineiro - a common brain factor underlying memory decline in older age. Stronger associations in older, but independent of genetic Alzheimer risk. Very interesting work using >10.000 MRI scan. LCBC - UiO biorxiv.org/content/10.110…

Very interesting from Didac Vidal Pineiro - MUCH higher reliability for structural neuroimaging measures with longer follow-up time rather than more follow-ups or higher n. 2.-year follow-up requires 4 times higher n than 6-year follow up. LCBC - UiO direct.mit.edu/imag/article/d…

Distinguishing Lifelong Individual Differences from Divergent Aging Trajectories of Adult Brain Volumes biorxiv.org/content/10.110…

New in Nature Medicine Education is not linked to slower memory or brain decline in aging. We analyzed 400,000 memory tests and 15,000 MRIs from 33 countries. Associations likely shaped by childhood schooling and development. LCBC - UiO Lifebrain rdcu.be/ex8iC

Check the latest from James Michael Roe A collaboration between Oslo and Berkeley!! Studying cortical thickness changes in relation to AB acumulation. We find that AB converters show less cortical thinning comparedto nonconverters. Much more in 👇👇👇🧠 biorxiv.org/content/10.110…

Using 4570 longitudinal MRIs + 1684 Aβ PET scans from cognitively healthy older adults, James Michael Roe find cortical thickness changed ≥7 years before PET-detectable Aβ. Those who later developed high Aβ already had thicker cortex & less thinning. @LCBC_uio biorxiv.org/content/10.110…

pnas: Small sex differences in brain aging, steeper decline in men in some regions although more women are diagnosed with AD. 12,638 longitudinal MRIs, 4,726 participants across 14 cohorts. Control for head-size, education, life-expectancy. LCBC - UiO pnas.org/doi/10.1073/pn…

Very impressed with Didac Vidal Pineiro's work in Nature Communications, the most thorough mapping of longitudinal memory-atrophy relationships in aging, showing global and memory-specific associations, growing stronger with age. Early access here: nature.com/articles/s4146… LCBC - UiO Lifebrain