Wonderful new paper by @LabSkiniotis Kobilka lab, Bryan Roth Sush Majumdar, Tao and many others! nature.com/articles/s4158…

Congrats to my many colleagues, past and present, who were involved in this work out TODAY in Nature Chemical Biology - great to see it finally published 🥳 many Twitterless + Alpay Burak Seven Haoqing Wang Tao Michael J. Robertson BryanRoth Susruta Majumdar Dror Lab @LabSkiniotis

In Nature with Kobilka Seva Katritch @LabSkiniotis Tao Ream Al-Hasani ريم الحسني BryanRoth and our postdocs Abdelfattah Faouzi, Ph. D. Haoqing Wang Saheem Zaidi Balazs Varga Manish K. Madasu Big shoutout J Diberto, Qu and Mclaughlinlab (UF) for bringing us home @ClinicPharmSTL nature.com/articles/s4158…

🚀 Excited to share our latest in Nat Comm! 🎉 "Structure-guided design of partial agonists at an opioid receptor" presents C6-Quino, a δOR partial agonist with oral activity & analgesic effects—avoiding δOR seizures & µOR effects! 🔗 nature.com/articles/s4146… #GPCR #DrugDiscovery