This must be tweeted every Halloween. I don’t make the rules

Matching patients to #ClinicalTrials is usually complex and time-consuming, often leaving patients unaware of potential treatment options. This study presents a custom fine-tuned language model that uses real-world patient data to automate trial matching, showing performance

In our recent paper accepted at NeurIPS 2024, my student, Rachel Si Yan Teo (rachtsy), uncovered a link between self-attention in transformers and kernel PCA. Specifically, Rachel demonstrates that self-attention projects its query vectors onto the principal component axes of

Very excited taking part in this dgppn.de/veranstaltunge… in a few weeks. You can still apply.

Study found a relatively high rate of remission and a paucity of relapse episodes within individuals followed up in an early intervention service for psychosis. ja.ma/48xMDPF

Most viewed in the last 7 days from JAMA Psychiatry: Which antipsychotics are associated with the most beneficial outcomes regarding cognitive function and, secondarily, quality of life and social functioning? ja.ma/3NOvlnG

Why any Alzheimer's definition needs a clinical-cognitive-biological approach. Biomarkers (ATN & others, i.e., proteomics) are pathological processes, not hallmarks of a unique disease. AD is a complex disease. Delighted to join this IWG in JAMA Neurology 👉bit.ly/3Ao79p1

I believe that the vast majority of people in this country are good and generous and honest and fair – and whether they are Democrats or Republicans or independents, they want those values reflected in their politics. That’s what we’ll get with Kamala Harris and Tim Walz – two

New preprint! Strong genetic overlap between severe mental disorders and blood metabolic markers. Fascinating patterns: opposite effect directions of the markers on major depression versus bipolar disorder and schizophrenia. tinyurl.com/metaboPsych. #metabolicpsychiatry

Having started my career in basic neuroscience research, I have always understood Alzheimer disease to mean the pathophysiology associated with amyloid plaques and tau tangles. As a clinician, I appreciate that the relationship between Alzheimer disease and cognitive impairment

🇨🇦 🇪🇺 ELLIS and @CIFAR are joining forces to expand the ELLIS PhD & Postdoctoral Program in AI CIFAR Fellows and Canada AI Chairs will join ELLIS advisors, connecting PhD students with top AI researchers across Europe & North America. Learn more here: bit.ly/4hFvurq

A scientist who successfully treated her own breast cancer by injecting the tumour with lab-grown viruses has sparked discussion about the ethics of self-experimentation go.nature.com/3NXqzEq

From a few weeks ago: it was such a privilege to work with the monks of Sera Jey monastery and install an EEG lab in the monastery!

With generalized teacher forcing (proceedings.mlr.press/v202/hess23a.h…) generative dynamical systems modeling becomes possible even for short fMRI time series, at scale, using a trick for inverting the (convolution) BOLD decoder model! New #neurips2024 paper!

📢 Computational Psychiatry Conference 2025: symposium abstract submission now open. 📢 We are excited to announce that #cpconf2025 will take place in Tübingen, Germany, 14-16 July 2025. We are now accepting symposium submissions!

According to dynamical systems, psychiatric disorders can be seen as energy landscapes with peaks and valleys. OCD has deep valleys where neural activity gets stuck, while schizophrenia has shallow valleys that let neural activity roam too freely, connecting unrelated ideas.

1 of 4 linked commentaries on dynamic connectivity in Imaging Neuroscience, by Diego Vidaurre: Dynamic functional connectivity: Why the controversy? doi.org/10.1162/imag_a…

Linking post-mortem cell-type distributions with the in vivo functional organization of the human cerebral cortex, as assessed through fMRI Xi-Han Zhang @AvramHolmes Kevin Anderson Sidhant Chopra Elvisha Dhamala Mark Gerstein Daniel Margulies Holmes Lab nature.com/articles/s4159…

My paper is out!! 🎉 "Opponent control of reinforcement by striatal dopamine and serotonin", nature Here, we show that dopamine and serotonin signals form a gas-brake system for reward in the mammalian brain 🧠 THREAD ⬇️ 1/n

Leaving twitter. You can follow the updates from my lab and me here: bsky.app/profile/thomas…