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Spatial Biology applications highlighting novel research, experimental models & computational tools investigating mechanisms in #Immunology #infection #cancer & application of novel #spatial #organoids #pathology #cellsignalling #GBM #Brain

This Wed May 22 at 3:30PM Doherty Institute, we'll highlight how we're using tissue spatial proteomics by Akoya Biosciences tech & other spatial tools to discover novel ways to boost anti-tumour immunity & kill brain cancer cells #GBM UniMelb MDHS bit.ly/4bl8Ssk #multiomic

Presenting our research at the WEHI Spatial Biology Symposium with talented scientists sharing a passion for the research nexus between biology & pathology #glioblastoma #brain #cancer #immunology Doherty Institute UniMelb MDHS

Congratulations to PhD student Philipp Graber on his first author review on ex vivo modeling of gliomas Childrens Cancer Institute UNSW Medicine & Health NanoMed buff.ly/3xfgHBo

Discover the future of 3D-omics! Our perspective aritcle explores how tissue clearing and AI with single-cell omics could revolutionize understanding of entire organs & organisms. Read the full article: nature.com/articles/s4159…

We share our review discussing several key studies investigating the immunosuppressive tumour microenvironment, with a focus on brain cancer​ doi.org/10.1016/j.immu… Marija Dinevska Theo Mantamadiotis @BrainCancerLab

"Reprogramming the brain tumour microenvironment to enhance anti-tumour immunity" - Looking forward to the opportunity to present our research #GBM #glioblastoma #brain #cancer #immunology #research UniMelb MDHS Doherty Institute

WEBINAR: To learn about #braincancer & how my lab uses @Akoyabio mIHC #spatialbiology tech to understand fundamental molecular & cellular mechanisms regulating the #tumormicroenvironment, register @ bit.ly/3AR8Mf1 UniMelb MDHS Doherty Institute #GBM #brain #cancer

Webinar fast approaching bit.ly/3AR8Mf1

Our latest out today nature! We revisit a century-old theory and show that metabolic gradients work hand-in-hand with genetic&signalling instructions to shape the embryo. Glucose isn't just an energy source, it acts as a major conductor of the body plan🍬 nature.com/articles/s4158…

Thanks Lluis & all Schuetzians! It's important to acknowledge Guenther Schuetz's contributions to pioneering research, which has allowed me & others to make new discoveries on how diseases develop in the brain, including the focus of my research on #braincancer #glioblastoma

Great to have the opportunity to present our research at The Brighton Tumour Microenvironment Conference, UK. One of the recurring themes focussed on #ECM remodelling & #cancer #immunology, in many different cancer types, including our own research on #glioblastoma #GBM

Following several presentations on how we use #spatialbiology to investigate the #immunology of #braincancer - also see our recent review on this topic shorturl.at/7pwV1 Samuel Widodo Marija Dinevska Marianna Rapsomaniki University of Melbourne Doherty Institute

Mice with an inducible nestin-CreER transgene targeting PI3K & PTEN develop brain tumors doi.org/10.1093/neuonc…. ~20% of mice also show tumours of the reproductive organs. Using #spatialbiology we describe the testis tumors, in the bioRxiv pre-print: doi.org/10.1101/2024.0…

Carcinogenesis: shorturl.at/6pvy6 Mice with targeted Pi3k-Pten mutations develop tumors resembling an aggressive form of sex cord stromal tumors. We describe the cell-of-origin, complex histopathology & using #spatialbiology, map immune cell infiltration of this rare cancer

The Who's Who of spatial biology in Australia & SE Asia at the WEHI Spatial Technology Symposium in Melbourne. A fabulous lineup of speakers & platform leaders highlighting the fast moving research & tech in #spatial #biology