A night retreat with the lab at Nahal Havarim, looking for scorpions on a full moon (one of the ones we found is called "Deathstalker"!!)

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1/5) Do males and females age differently? What happens to our metabolism as we age? Is it reversible? Using the turquoise killifish, we identified sex-specific regulation of metabolic health and lifespan by AMP biosynthesis. Our preprint: biorxiv.org/content/10.110…

Itai and Eitan got the cover! :) Check out the latest issue of CSH Protocols, in which we describe a step-by-step guide for efficient CRISPR–Cas9 genome editing in killifish: cshprotocols.cshlp.org/content/2023/2… The 'blueprint' represents the versatility of this experimental model system!

Great to present our work at #IBS2023 and the workshop single cell network Israel (scIL).

I presented a talk at the notho-2023.be meeting on the last Friday. I was waiting and afraid of this for almost a month, but in the end, I bit enjoyed being on the stage🙂. Thanks to the people who were with me on this journey. Itamar Harel

Excited to share our new paper Developmental Cell on how manipulating AMP biosynthesis can extend vertebrate lifespan! Huge congrats to Tehila Atlan, Gwendoline Astre, and all the authors! It was a fun collaboration with @Joris_Deelen & Levanon Lab! doi.org/10.1016/j.devc… A 🧵...

The ultimate sacrifice? In a beautiful preprint led by Eitan and Tehila, we demonstrate that ablating the germline in vertebrates has a sex-specific effect, significantly prolonging male lifespan while conferring exceptional stress resistance in females! biorxiv.org/content/10.110…

The ultimate sacrifice? 🔥Amazing work Nature Aging by Tehila and Eitan, demonstrating that the germline regulates vertebrate longevity and somatic repair! A fun collaboration with Sagiv Shifman, William J. Greenleaf, Oren Ram & Ehud Cohen! Follow & retweet!! nature.com/articles/s4358…