nature.com/articles/s4158…

We thank NCI for supporting our work in 3D cancer genomics! This work was led by our grad student Katie Mortenson, co-supervised by K-T Varley, with close collaborations from Yang Liu, Jay Gertz , and Swneke Bailey.

So thrilled to have Mathieu Rousseau join our team McGillThoracic McGill Surgery! Tremendous opportunity for us to grow as a group and for our fellows to benefit from his approach and experience! Canadian Association of Thoracic Surgeons

An excellent talk!

Last week was an eventful week for the Division of Thoracic and Upper Gastrointestinal Surgery. We hosted our annual TREAT Canada in person meeting and the 7th annual symposium on Upper GI cancers. It was an honour to welcome so many incredible speakers Lorenzo Ferri MD PhD

We kicked off the TREAT meeting with a ‘welcome and project overview’ by Dr. Ferri Lorenzo Ferri MD PhD and ‘Understanding and improving response to treatment in oesophagogastric cancer’ by Dr. Tim Underwood Tim Underwood

During Work Package 1 session of TREAT Canada, Drs. Cools and Yeung have delivered talks on the ‘workflow and optimization - the MGH experience’ and an ‘ Update from Toronto General Hospital Site’

WP3 of TREAT, speakers Mingyang Iris Kong Sanjima have talked about ‘Neuroendocrine differentiation as a mechanism of chemotherapy resistance and how to target it’ and ‘Modelling tumour-micro environment interactions to assess novel treatment approaches’

Neoadjuvant Avelumab (PD-L1) + Docetaxel triplet in gastro esophageal adenocarcinoma- a highly effective regimen. It’s been a long 8 years since we launched this trial, good to finally see in print! cell.com/cell-reports-m…

Great seeing this manuscript in print on patient-specific esophagus cancer-organ chip. Complete clinical mimicry Excellent work by ⁦Sanjima⁩ ⁦Research Institute of the MUHC (The Institute)⁩ with collaboration with ⁦Wyss Institute⁩ ⁦Don Ingber⁩ …nslational-medicine.biomedcentral.com/articles/10.11…

So excited to see this paper on the stromal changes driving Barrett’s Esophagus progression to Cancer. A Herculean effort effort integrating scRNASeq/CODEX/ECM proteomics. Concerted changes in Epithelium and Stroma: a multi-scale, multi-omics... sciencedirect.com/science/articl…

Right on time for #sarcoma awareness month! Happy to share that our most recent work just published in Nature Communications 🎉 In this study we discover that #EZHIP is an ectopically expressed oncogene in a subset of high-grade #osteosarcoma tumors. nature.com/articles/s4146…

nature.com/articles/s4146…

We are looking for a researcher in cell biology and/or bioengineering to join a dynamic and highly collaborative group of scientists McGillThoracic studying lung and esophageal cancer with close collaboration with the Rosalind & Morris Goodman Cancer Institute and the McGill Department of Biomedical Engineering.

🔬 Dr. Lorenzo Ferri (The Institute) and Dr. Donald Ingber (Harvard) created an organ-on-a-chip that predicts chemotherapy response — a breakthrough in precision oncology! Centre universitaire de santé McGill Wyss Institute 👉 rimuhc.ca/-/an-organ-chi…

Wrote a commentary with jonathan Cools on an interesting finding that cancer patients have long term immune deficits despite curing their cancer! When do these deficits start? Before the cancer starts? Once the tumor grows? Lots of interesting Qs. ashpublications.org/blood/article/…

🔬 Une étude de L’Institut et de l’Institut Lady Davis révèle de nouveaux mécanismes de l’ostéosarcome, cancer des os fréquent chez les jeunes. Vers des thérapies plus ciblées. Centre universitaire de santé McGill McGill Medicine and Health Sciences ➡️ rimuhc.ca/fr/-/une-etude…

Nice to see our work on patient specific esophageal cancer organ-chips as a platform for functional precision oncology featured in ⁦CBC News⁩. With support from ⁦Research at Canadian Cancer Society⁩⁩ ⁦CIHR⁩ we hope to bring this to patients soon! cbc.ca/news/health/ca…

TREAT-CANADA CCS-CIHR Breakthrough Grant all team meeting getting started in a soggy Montreal morning. Overcoming therapy resistance in gastro-esophageal cancer is a team sport. ⁦Research at Canadian Cancer Society⁩ ⁦CIHR⁩

That concludes today’s meeting, thank you to all our speakers and attendees for an insightful session! Lorenzo Ferri MD PhD Greta Evaristo, MD Sanjima Swneke Bailey MyGutFeeling-Stomach Cancer Foundation of Canada Dae-Kyum Kim