The lack of diversity in the genomics workforce is a consequence of a larger set of societal barriers and this lack of diversity directly hinders progress in genomics.

Prediction of type 2 diabetes using genome-wide polygenic risk score and metabolic profiles: A machine learning analysis of population-based 10-year prospective cohort study pubmed.ncbi.nlm.nih.gov/36462406/?utm_…

🚨 ONLINE Nature Genetics 📰 Genomic innovation and regulatory rewiring during evolution of the cotton genus Gossypium 🧑‍🤝‍🧑 Jonathan F. Wendel, Xianlong Zhang and team 👇🏿 go.nature.com/3PbccfH

'Whole genome sequencing could help patients living with cancer of unknown primary." Dr Bezecny from Chorley & Royal Preston NHS Blackpool Teaching Hospitals 💙🌈 highlights a new test added to the National Genomic Test Directory that could help patients get more effective treatments. NWGMSA The North West Genomic Laboratory Hub

see the review of the Updated KDIGO Guideline for Managing Diabetes in Patients with Chronic Kidney Disease jwatch.org/na55698/2023/0… KDIGO

Let’s talk about proteins whose abundance generally does not correlate the abundance of the transcripts that templates them. Give examples.

🚨Data alert🚨 Genome-wide summary statistics for all 2,923 plasma proteins measured by Olink Explore 1536 and Expansion assays (a.k.a. Olink Explore 3072) in 2,887 participants is now available on omicscience.org/apps/olinkpgwa…

#mdpibrainsci New Special Issue Open for Submission! Reviews in Neural Control of Peripheral Function edited by Dr. Abirami Veluchamy and Dr. Sundararajan Srinivasan mdpi.com/si/170098 MDPI MDPI Medicine & Pharmacology @Scilit_MDPI #neuroscience #brain #PeripheralFunction

Excited to get this preprint out there showcasing an collaboration pooling data + expertise across 🇮🇳🏴󠁧󠁢󠁳󠁣󠁴󠁿🏴󠁧󠁢󠁥󠁮󠁧󠁿@Theodysse Andrew Brown Dr.V.Mohan Sarah Finer Rohini Mathur UoD Medicine Adem yesuf Sundararajan Srinivasan Colin Palmer The Scottish Health Research Register & Biobank medrxiv.org/content/10.110…

Postdoc is conceptually different from a #PhD position. Below are some key points to keep in mind before starting postdoc. 1️⃣ The harsh reality of being a postdoc: 1. Postdoc is a contractual (not educational) position. Your postdoc duties are defined by your contract &

Our paper in Diabetes Care, a research journal of the ADA 🌟 describing the disparity in heritability estimates of age at diagnosis and explains the polygenic variation in South Indians. INSPIRED Colin Palmer Dr.Mohan's Diabetes Ewan Pearson Dr.V.Mohan Moneeza K Siddiqui UoD Medicine doi.org/10.2337/dc23-0…

Genetic risk factors of schizophrenia and their effect sizes--common variants, rare variants, CNVs and polygenic risk. I love the addition of the effect size of the top 1% of polygenic risk to the plot. It highlights the importance of cumulative risk of common variants and

ENCODE-rE2G: An encyclopedia of enhancer-gene regulatory interactions in the human genome biorxiv.org/content/10.110…

In this week's post (gwasstories.com/p/how-a-jumpin…), I write about a fascinating discovery by Po-Ru Loh, Steve McCarroll and team of a retrotransposon within ASIP (encodes agouti related protein) shaped human skin color evolution. Kamitaki et al. Nat Gen 2024 nature.com/articles/s4158…

📢 The Polygenic Score (PGS) Catalog has been updated, including data added from multi-ancestry or non-European populations and a PGS Catalog calculator. The project is a collaborative effort between Cambridge University, EMBL-EBI and NHGRI-EBI GWAS Catalog. Learn more: hubs.li/Q02Rdfc60

RCT of Vitamin D shows a large impact on clinically isolated syndrome. shorturl.at/QsZIj This is consistent with Mendelian randomization evidence published in 2016 and should prompt clinicians to ensure vitamin D repletion in those at risk of MS. shorturl.at/adRiQ

Proteome-wide observational, Mendelian randomization, and cocol analyses for myoc infarction, ischemic stroke, and heart failure in UK and China Kadoorie biobanks. 👉strongest associations across methods, biobanks, endpoints: FURIN, PROCR, GFG5, MMP12 📰nature.com/articles/s4416…

I had fun contributing (in a minor way) to this perspectives piece on the importance of family-based biobanks led by @nm_davies and Matt Keller . Important message for funders and those in a position to influence the next generation of big genetic studies.

The authors suggest that data from longitudinal proteomic profiling of women years after gestational #diabetes provides insights for clinical decisions and early lifestyle interventions #T2D JCI insight insight.jci.org/articles/view/…

Fearless in unity. Boundless in strength. India’s shield is her people. There’s no room for terrorism in this world. We’re ONE TEAM! Jai Hind 🇮🇳 #OperationSindoor