After more than a decade at the fabulous NIH Intramural Program, happy to share that I have recently joined Yale Department of Immunobiology as Professor of Immunobiology. I will also serve as the founding director of the soon-to-be-launched Yale Center for Systems and Engineering Immunology (CSEI).👇

Very happy to see our paper out in Journal of Clinical Investigation, with Hiromitsu Asashima, Tomokazu Sumida,David Hafler. We show TIGIT expression is down in B cells from MS patients, mediated by TCF4 dysregulation, which then impacts Tfh phenotypes. #humanimmunology jci.org/articles/view/…

Neurosurgeon fights his brain tumor! gofund.me/f16cba35

Thrilled to see our study out in Science Translational Medicine with Tomomi Yoshida Liliana Elisa Lucca Carrie Lucas @EricVerdin Tomokazu Sumida David Hafler during my time Yale School of Medicine. We took a deep dive into the role of HDAC7 in Tregs in the context of #MultipleSclerosis risk.🧵science.org/doi/pdf/10.112…

Great paper. I strongly agree that causal gene regulatory network inference (i.e. where u can actually claim gene A causally and directly regulates gene B) using mRNA alone is impossible IMHO. Even from perturbation expts. I think this is impossible. 1/

Thank you, Yongjin! This has been one of the best collaborations I've ever had. I’m so proud to be working with you, Liang, and Matt! Let’s keep up the great work together.

In a new study, researchers utilize #epigenomic and #transcriptomic profiling of people with relapsing-remitting #MultipleSclerosis to identify pathways involved in regulatory #Tcell dysfunction in autoimmunity. Tomokazu Sumida David Hafler scim.ag/8eO