Forschende des ECRC berichten in JCI insight von einer neuartigen Genschere, die möglicherweise den Weg für eine Therapie der #Muskeldystrophie ebnet. Mehr: mdc-berlin.de/de/news/press/… #mdcBerlin @SimoneSpuler Charité - Universitätsmedizin Berlin

#Cover: Base editing repairs an SGCA mutation in human primary muscle #StemCells: buff.ly/3vmpmvH Image: patient-derived primary muscle stem cells, fused into multinucleated myotubes in vitro following gene repair by base editing @SimoneSpuler Charité - Universitätsmedizin Berlin #Therapeutics

This gut organoid reveals a novel function of NF-kB in cell differentiation & stem cell maintenance: More on its interaction with the Wnt signaling pathway in a new paper by Brischetto and Schmidt-Ullrich (Scheidereit lab) from #mdcBerlin in Development! doi.org/10.1242/dev.19…

I am proud to share our latest work sciencedirect.com/science/articl… showing how mRNA-based delivery of @CRISPR tools leads to highly efficient gene editing in human muscle stem cells! Special thanks to my great colleagues @ChrisStadelmann Helena Escobar and our supervisor @SimoneSpuler.

And Silvia Di Francescantonio !

ICYMI: mRNA to introduce gene editor into human muscle stem cells: lnkd.in/eu3HSGES Mentioned: @SimoneSpuler, Helena Escobar, @ChrisStadelmann, Silvia Di Francescantonio, Max Delbrück Center, Charité - Universitätsmedizin Berlin #research #GeneEditing

#Geneediting #muscle #stemcells – promising approach to treat muscle disease. Image & research by @ChrisStadelmann & Silvia Di Francescantonio, et al Helena Escobar @SimoneSpuler @mdcBerlin Charité - Universitätsmedizin Berlin Helmholtz in Molecular Therapy. More on bpod.mrc.ac.uk/archive/2022/4… with MRC Laboratory of Medical Sciences (LMS) & Ruth Williams

Very happy to have our work featured on the cover of Mol Ther - Nucleic Acids. Beautiful image by Silvia Di Francescantonio. mRNA-mediated delivery of CRISPR tools to edit human muscle stem cells. @SimoneSpuler @ChrisStadelmann. Max Delbrück Center Molecular Therapy

A new issue of @moltherapy Nucleic Acids (#MTNA) is out! On the Cover: The cover image shows human primary muscle #stemcells fused into multinucleated myotubes following mRNA-mediated #genomeediting. bit.ly/3NZsJSt

Recapitulating the complex growth of a mouse embryo in vitro.

Buon viaggio papà.

The Bio-Imaging West Africa Training workshop 2022 organised by the West Africa Microscopy and Bio-image Analysis Network (WAMBIAN) at WACCBIP commences.

Final day of the BioImagingWestAfrica2022. Here four of the groups sharing their analysis pipelines to solve the challenges we gave them. Super impressive how far they got in 1 1/2 days! 🔝 🔝

We are hiring! Lab Project Manager in Egomes lab at iMM COLife. Apply until 28th of November. More info drive.google.com/file/d/1sUYKub…

Happy to receive an ERC Proof-of-Concept to developt some cool tech to fight neuromuscular disorders. erc.europa.eu/news-events/ne… thanks to Afonso Malheiro and Katharina Hennig to make this possible! and European Research Council (ERC) and iMM for support

Edgar Gomes Gomes Lab @[email protected] and his team @immolecular medicina were awarded with a Proof of Concept grant from European Research Council (ERC) to develop a technology that will mimic neuromuscular disorders and contribute to accelerate the discovery of novel drugs and therapeutic targets. #CAML