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Striking activity with ABBV-706 SEZ6 ADC in high grade neuroendocrine cancer (NECs) where active therapies are urgently needed. Thank you to the patients and their families. Alissa Cooper, MD #LCSM

Simultaneous publication here The Lancet thelancet.com/journals/lance…

Dr. Xinghao Ai presents Phase 2 ZG006 10 vs 30 mg 3L+ ES-SCLC at #ASCO25 ZG006 (Alvetamig) demonstrated high ORR (62.5% vs 58.3%) q2w in heavily pretx SCLC ⭐️Rapid response ➡️seen at 6w scans ❗️CRS & ICANS increased w/ 30 mg dose 🚨DLL3+ not required for study entry

#DeLLphi304 results as presented by Charlie Rudin here at #ASCO25 — how best to sequence our treatment options in ES-SCLC after disease progression on chemoimmunotherapy? SmallCellSMASHERS

Dr. Charlie Rudin Charlie Rudin Memorial Sloan Kettering Cancer Center presents long-awaited DeLLphi-304 tarlatamab vs chemotx in ES-SCLC at #ASCO25. ⭐️5+ month ⬆️ mOS (13.6 vs 8.3 mo) ⭐️Early PFS separation ⭐️Awaiting maturity (11m F/U) ❗️ICANS, CRS: most G1 ⚠️Minority rec’d lurbi ✅New 2L SOC

Take a BiTE out of this tarlatamab roadmap. More to come for our patients with small cell lung cancer! 🍎 #ASCO25 ASCO SmallCellSMASHERS OncoAlert

💡 After 2 oral presentations that definitively change the treatment landscape and impacts in survival for patients with ES-SCLC (any of them, if not both, should have been plenary ASCO this year), the key question here is: when will we have access to lurbinectedin and

Thankful to God, my family, amazing mentors Nasser Hanna Christine Lovly, MD, PhD, FASCO & pt advocate Jill Feldman, our patients & their families, SmallCellSMASHERS, The Shields Lab & collaborators, & IU Simon Comprehensive Cancer Center for your support, strength, & encouragement! Conquer Cancer, the ASCO Foundation #CDA #ASCO25

Our MD Anderson Cancer Center thoracic oncology rotation journal club for the fellows is about to be 🔥 🔥 #ASCO25

Join us for a Facebook Live on 6/20, w/ Michael Gieske, M.D. (St. Elizabeth) & Nasser Hanna, MD (IU School of Medicine) where they will present on Lung Cancer Screening: Eligibility, Engaging Healthcare Systems, and Impact for Lung Cancer facebook.com/lungevity @sclcsmashers Misty Dawn Shields

True joy to be a guest on Upstage Lung Cancer Upstage Lung Cancer podcast focused on HOPE ⭐️ in #SCLC! Host Hildy Grossman, colleagues Dusty Donaldson Dusty Joy Donaldson LiveLung, SCLC survivor Maida Mangiameli & Ann Fish-Steagall Ann Steagall LUNGevity Foundation SmallCellSMASHERS Link 🔗🎧soon!

Thank you to Live Lung LiveLung for sharing my life story and my “why.” #LCSM SmallCellSMASHERS

Thank you Live Lung LiveLung for shedding light 💡 on such an important topic. The search for biomarkers in lung cancer, especially SCLC, is of utmost importance. How do we get the RIGHT therapy for the RIGHT patient to improve outcomes & maximize quality & quantity of life?

Thank you to Live Lung LiveLung for highlighting the need to expand lung cancer screening criteria - to help capture ALL “at risk” individuals, while balancing the risks of potential harm or false positives. Raymond Osarogiagbon, MBBS, FACP Nasser Hanna Michael Gieske, M.D. Jeff Yang MD FACS ALCSI

Thank you to Live Lung LiveLung to helping spread the word on how tissue biopsies can be sometimes limited due to crush artifact & how liquid biopsies may help improve care for patients diagnosed with #SCLC #clinicaltrials #genomics Mya Tran SmallCellSMASHERS

Honored to be invited to join the IASLC Rare Tumors Committee! Thankful for the opportunity to contribute to this amazing committee and to help impact education, outreach, & research surrounding #SCLC. SmallCellSMASHERS LUNGevity Foundation #LCSM

Thank you to Dr. Nasser Hanna (Nasser Hanna IU Simon Comprehensive Cancer Center) & Dr. Michael Gieske (Michael Gieske, M.D. St. Elizabeth) for a wonderful SmallCellSMASHERS Fireside chat today on lung cancer screening! LUNGevity Foundation The White Ribbon Project™ Jeff Yang MD FACS Chris Draft Lecia Sequist, MD, MPH ALCSI Ann Steagall

3 weeks after ASCO25, let’s digest the data from the landmark DeLLphi-304 trial published in NEJM that changed the >30 years SoC in recurrent #SCLC from immunobiology and clinical standpoints: 🧵 1/15 #some #LCSM @ASCO IASLC ESMO - Eur. Oncology ETOP IBCSG Partners Foundation EORTC SmallCellSMASHERS

This is 40! Thank you to my sweet friends & family for ALL the amazing messages, gifts, and memories to make my day so special! Here’s to the next chapter! #imsoold

Thank you Upstage Lung Cancer for sharing the exciting progress that brings HOPE in #SCLC! Listen to the podcast episode : 🔗 upstagelungcancer.org/podcasts/progr… SmallCellSMASHERS LUNGevity Foundation Dusty Joy Donaldson LiveLung Ann Steagall Hildy Grossman #LCSM