Anti-TL1-a 3.0! Duvakitug demonstrated efficacy primarily for endoscopic endpoints in mod-severe #crohnsdisease in a first of its kind in #IBD basket trial (parallel UC, CD). Well tolerated Vipul Jairath MBChB DPhil #DDW2025 #IBD

#DDW2025 SQ induction Guselkumab in UC #ASTRO Millie Long 🔺GUS 400mg SC q4w x3 vs placebo -> GUS 100mg SC q8w or 200mg SC q4w vs placebo 🔺Wk12 Gus vs placebo ✔️ClinRem 27% vs 6% ✔️EndoImprov 37% vs 13% ✔️ClinResp 65% vs 34% ✔️HEMI 30% vs 11% ⚠️🟰QUASAR IV induction data !

Slots Still Available! This Wed, May 7 – LIVE from Cleveland Clinic: RECTOVAGINAL FISTULAS. Join David Liska Arielle Kanters Anna Spivak Tracy Hull Olga Lavryk, MD Cleveland Clinic MD for this CME MOC event.  Register bit.ly/LIVECC2025

Florian Rieder promising phase 2a STENOVA interim results TGFb receptor antagonist, AGMB129, in symptomatic >/= 1 TI stricture. 👉TGF-b major pro-fibrotic growth factor. ➡️ mean 17.5 yrs CD, fcal 373, SESCD7 ➡️sig ⬇️ fibrotic &inflamm pathway ➡️improved stricture passability

No better person than Florian Rieder to present the results of the #STENOVA TRIAL. #DDW2025 #antifibrotics Jean-Frederic Colombel Vipul Jairath MBChB DPhil Y-ECCO Axel Dignass Remo Panaccione, MD, FRCPC Miguel Regueiro Sophie Restellini Aline Charabaty, MD, FACG, AGAF Anja Poulsen Shomron Ben-Horin

#DDW2025 Real world PRO w Risankizumab in #Crohns #ASPIRE-CD 🔺286 pts, CD duration 14yrs, 75% bioexposed, 1/3 w stricture &/or fistula 🔺RISA IV induction wks 0,4,8 ✅Sympt at wks 2,4,12 ⬇️Average & worst Abdo pain, urgency, diarrhea as early as week 2 & further ⬇️ by week 12

What a weekend at #DDW2025! 🥳 SAIA proudly hosted two events that brought patients, caregivers & clinicians together to share insights & experiences that are shaping a more equitable future in IBD care. A great reminder on how far we've come & how much further we can go! 🙏🏽💜

🚨We are excited to host Dr. Axel Dignass as our Global IBD Visiting Professor Cleveland Clinic next week. 🗓️Join us on Tuesday, June 17th, 7AM EST for a live virtual event. Register FREE here👉: bit.ly/GlobalVP-2025-… Miguel Regueiro Michelle Kim Florian Rieder Sara El Ouali MD

‼️Anyone interested in organ fibrosis please join us for the Keystone Fibrosis Symposium 2026 ‘Cross Organ Pathology and Pathways to Clinical Development’ ‼️Introduction video can be found here url.avanan.click/v2/r01/___http…. Registration 👉🏻 keysym.us/KSFibrosis26 Suzanne Devkota

🙋‍♀️Do you know about Updated SAR consensus defining small bowel Crohn’s strictures on CT/MRE❓ ➡️ Pre-stenotic dilation no longer at 3cm for a cut off. Is now 2.5cm‼️ Florian Rieder Dominik Bettenworth Anja Poulsen Parakkal Deepak MD, MS, FACG JordiRimola David Bruining doi.org/10.1148/radiol…

Welcome to the Cleveland Clinic global #IBD group Anthony de Buck 🌍 Looking forward to working together across all sites Cleveland Clinic London Cleveland Clinic Abu Dhabi Cleveland Clinic Florida Miguel Regueiro Florian Rieder Charlie Murray Asad ur Rahman, MD, FACP Steven D Wexner MD, PhD Marylise Boutros

Congratulations Anthony de Buck

BIG honor to host Kerri (Prof. Kerri Novak) from U Calgary as our 🌎 IBD visiting professor at Cleveland Clinic #OneIBD. A humble and really funny giant in the field of intestinal ultrasound. Katie Falloon Anthony de Buck David Liska Miguel Regueiro Stephen Lupe Suha Abushamma, MD

Florian Rieder Kerri U Calgary Cleveland Clinic Katie Falloon Anthony de Buck David Liska Miguel Regueiro Stephen Lupe Suha Abushamma, MD Stefan Holubar MD MS Ido Veisman Pranab Mukherjee Steven D Wexner MD, PhD Sara El Ouali MD An incredible physician, but much more: an amazing human being!!!

What an incredible honor to host you Kerri, thank you for taking the time to be with us, thanks for the wonderful presentations, and all the precious advice and wisdom!

👉🏻👉🏿Not only some, but ALL aspects of fibrosis, presented by international top leaders in phenomenal location 🇩🇪. Not to miss event. Register here: falkfoundation.org/en/topics/colo…. #GerhardRogler, our excellent faculty and myself wish you can join us! 👈🏿👈🏻 Miguel Regueiro Suzanne Devkota

Amazing kick-off for the yearly #STARConsortium operational team meeting in Cleveland, OH!. Global leadership in stricturing #Crohns disease&top science while caring for and respecting each other. Grateful for this amazing group working to improve #IBD patients’ lives Helmsley Charitable Trust

From mechanisms to medicines in stricturing #Crohns disease: The #STARConsortium yearly meeting Cleveland Clinic. International leaders, all dedicated to progress in testing anti-stricture therapies Miguel Regueiro Helmsley Charitable Trust Jacob Kurowski Christina Ha MD Meena Bewtra Joseph Sleiman, MD, FACP

Cleveland Clinic Colorectal fellowship. Where else can a trainee get this amazing experience! Today we had the legendary Dr Tracy Hull deliver the definitive talk on RVF. Our dept travels the country/world disseminating knowledge. Our fellows benefit from them on a daily basis!