ICYMI in Cancer Discovery - work by #AACR24 plenary speaker Peter Sorger: The Spatial Landscape of Progression and #Immunoediting in Primary #Melanoma at #Singlecell Resolution doi.org/10.1158/2159-8… Ajit Johnson Nirmal Harvard Medical School NCI Human Tumor Atlas Network

PUBLICATION ALERT: Congratulations to Dr. Jennifer Guerriero, PhD and cross-institutional team at @brighamwomens, @danafarber and Harvard Medical School led by Drs. Peter Sorger, Mittendorf and Sandro Santagata, MD PhD!
📄 Read the publication here: nature.com/articles/s4152…
#spatialbiology #breastcancer #HER2

pubmed.ncbi.nlm.nih.gov/36669472/

pubmed.ncbi.nlm.nih.gov/36669472/ Thanks!

Wonderful to be selected for the Best of Cell 2023 - 'Multiplexed 3D atlas of state transitions and immune interactions in colorectal cancer' - NCI Human Tumor Atlas Network #HTAN . Cell.

Congratulations!!! to Jia-Ren Lin, Shu Wang, Shannon Coy, Yu-An Chen, Clarence

2D & 3D multiplexed subcellular profiling of nuclear instability in cancer biorxiv.org/content/10.110…: Our pre-print on nuclear envelope rupture in cancer - tools to map NE rupture and GBM cell state and lineage in tissues; + high-res 3D tissue imaging. Congrats Shannon Coy + Team.

Free-access link to our #ADC targets in #braintumors article out in SNO Congrats to Shannon Coy and our excellent collaborators for identifying the potential for label extension of FDA-approved ADC for rare and common #braintumors
BWH Neuropathology

academic.oup.com/neuro-oncology…

Fabulous tale of successful bench-to-bedside translation by Sandro Santagata, MD PhD — an absolute must-read for folks interested in drug discovery for rare diseases. linkedin.com/pulse/importan…

Thanks for highlighting this Anirban Maitra! It has been quite a journey and congratulations to the entire team from the beginning all the way through this practice changing study. Posted some reflections on this decade of work in an article on LinkedIn
linkedin.com/feed/update/ur…

🌟Today in Nature Cancer, we present an advance in #ColorectalCancer and #SpatialBiology !
Our study reveals the power of multimodal imaging for deeper molecular insights. Congrats Jia-Ren Lin, Yu-An Chen, RareCyte, Inc., Sandro Santagata, MD PhD, and Peter Sorger! 🧵
nature.com/articles/s4301…

A team led by Ludwig Harvard Medical School's Sandro Santagata, Peter Sorger, Jia-Ren Lin & Yu-An Chen developed a technology to integrate 'multiplex imaging', confined so far to research labs, with standardized methods of microscopy employed in clinical pathology. bit.ly/3Pr7MU4

Out today! In Nature Cancer : Integrating multiplexed IF + HE (IF-HE) for high performance tissue biomarkers. Integrating molecular info & #DigitalPathology will be key for diagnostics & research nature.com/articles/s4301… Congrats Jia-Ren Lin, Yu-An Chen, Danny Campton, RareCyte, Inc.!

Wonderful talk today by Jennifer Lundberg Jennifer Bailey Lundberg. Enjoyed our panel discussion on studying adenosine therapies in mouse and human tissues, and learning how to bring these drugs to pancreatic cancer and brain tumors. #pdac #GBM

Thank you Egle Kvedaraite . Enjoyed your very exciting talk on IBD and LCH!! Congratulations on the exceptional work!!

CONGRATULATIONS!!

Interested in exploring multiplex imaging data generated by #HTAN ? Lean more about #datavisualization with Minerva: docs.humantumoratlas.org/open_access/mi…

Thank you for inviting me to this fantastic symposium hosted by Van Andel Institute (VAI)!

Later this month (5/24), join us for a nature hosted webinar by Peter Sorger (@harvardmed) and learn how the Orion #spatialbiology imaging platform was used to identify prognostic signatures of #colorectalcancer : Save your seat! ➡️workcast.com/register?cpak=…

💡 Great insights in this Cancer Cell study showing that 'lymphonets' create a spatial environment supportive of CD8+ #Tcell anti-tumor responses. #lymphocytes Tweetorial ⬇️🧵

Online Now: Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinoma dlvr.it/SmmGxz