🚨🚨The GRC on Intrinsically Disordered Proteins #IDPs is coming up!! 🍝🧵🏔️ June 23 - 28, 2024 at beautiful Les Diablerets Switzerland. Come join us - but apply soon - spaces are running out! Details here: grc.org/intrinsically-… - follow us for more info on the program!

Check out our first pre-print, now up on ChemRxiv! A great collaboration with The Wilson Group. Peptide Macrocyclization via Intramolecular Interception of Visible-Light-Mediated Desulfurization chemrxiv.org/engage/chemrxi…

Very pleased to see our Spidr Idp paper on constrained N-Myc peptides out ChemBioChem from Robert Dawber with Megan Wright The Wilson Group and Bayliss Lab …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/cb…

Pleased to see this published Molecular Neurodegeneration. We summarise peptide-based approaches to directly target/modulate alpha-synuclein aggregation and toxicity, a major factor and key diagnostic hallmark of #Parkinsons disease & related Synucleinopathies. Scott Allen rdcu.be/dqDn8

Interested in understanding how and why IDRs matter for cellular function? Birthe B. Kragelund and I took a deep dive into this question and – with excellent feedback and critiques from colleagues & our amazing editor – put together our perspective on this: nature.com/articles/s4158…

Reminding all disordered protein🍝fans that the Gordon Research Conference on IDPs is still accepting applications! Please register soon since space is limited: grc.org/intrinsically-…… (...and this would be the view from your hotel room window)

Listen to our podcast episode on action and progress in cancer diagnosis and treatment.

Come by my poster, B174, at #cellbio2023 to learn about our exciting story surrounding Aurora A kinase. We’re very proud of the work from myself and the fantastic Spidr Idp team!

Registration is open now for Early Career Researcher Meeting: Structures and Probes of Intrinsically Disordered Regions, 10 June 2024 in Leeds! Keynote Speakers: Prof. Peter Tompa (VIB-VUB Center for Structural Biology) and Dr Markus Schade (AstraZeneca) spidr-slola.com/early-career-r…

Sign up for this meeting - its going to be super.

Jack’s talk has started! Pint of Science UK

Researchers at Uni of Birmingham, University of Bristol and University of Leeds successfully demonstrated a route by which peptides could be modified to make them promising reagents for disease diagnostics and drug discovery: birmingham.ac.uk/news/2024/pept… UoBChemistry The Wilson Group Engineering and Physical Sciences Research Council

Great range of speakers at our early career researcher meeting in Leeds with plenty of PhD and postdoctoral presenters.

Less than two weeks to go for the IDP GRC!! Program is in place (grc.org/intrinsically-…), with some updates coming soon. See you in beautiful Les Diablerets on June 23rd (or 22nd if you're attending the GRS)!!! 🍝⛰️🥾🚵‍♀️

We are looking to recurit a research associate as part of our ongoing SPIDR project on cell permeable PPI inhibitors in The Wilson Group jobs.ac.uk/job/DIF480/res…

New paper from our team using smFRET MS and cryoEM to see SurA delivering OMPs to BAM. Well done all - proud to work with you all! rdcu.be/dSDfs.

Delighted to be at EMBL for my first EMBO chemical biology workshop.

Check out this new collaborative SPiDR preprint with Megan Wright, Bayliss Lab and The Wilson Group. Constrained TACC3 peptidomimetics for a non-canonical protein-protein interface elucidate allosteric communication in Aurora-A Kinase | ChemRxiv - go.shr.lc/47ohUDY

Super sessions at the cell cycle kinases meeting organised by our very own Richard Bayliss Bayliss Lab Megan Wright and Jenny Miles in Leeds this afternoon.

Check out this exciting work incoporating synthetic chemistry, cryoEM and EPR to probe TRPC5 channels