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improved #bovine #mastitis treatment using designer #endolysin in #streptococcus uberis #mouse model #Researchpaper with E. Meyer in SpringerMicrobiology : bit.ly/LysinMastitis #antibiotic #bacteria #infectious #disease #sustainable #agriculture #phage #protein #engineering

Exploring our views on emerging #RNA analysis #technologies with tremendous value to both #fundamental and #applied #phage #research. review in Current Opinion in Microbiology: bit.ly/RNAtech #RNAseq #bacteria #molecular #microbiology #transcriptome #SynBio

Systematic strategy to decipher #phage-mediated #bacteria takeover using Grad-seq (gradient fractionation of #protein complexes coupled with #RNAseq & #proteomics) reveals phage #peptide modulating bacterial protein synthesis machinery Nature Microbiology : nature.com/articles/s4156…

Exploring our views on the impact of Post Translational Modifications elicited by #phage to rapidly finetune #bacteria #metabolism during #infection . Review with vera van noort in Current Opinion in #Microbiology : bit.ly/phagePTM #bioinformatics #alphafold #omics

New insights on intricate & diverse #gene #expression regulation mechanisms of different #pseudomonas aeruginosa #phage clades, using our ONT-cappable #sequencing. Proud of this #publication in microLife bit.ly/ONTcap-phage #transcription #microbiology #BIONICBACTERIA

20y of dedication/perseverance by Jean-Paul Pirnay , Maya Merabishvili & team to make #phagetherapy a reality. A good moment to say thank you for our 30th joint publication.

Microbes are crucial to our planet and well-being but go unnoticed. They provide food, medicines, clean water & help with climate change. The International Microbiology Literacy Initiative (IMiLI) aims to educate society about the importance of microbes: doi.org/10.1111/1751-7…

#Pseudomonas #protein PlzR regulators type IV #pili assembly in a c-di-GMP manner by PilZ/B #interaction. Check our #publication in Nature Communications nature.com/articles/s4146… #microbiology #motility #bacteria #AMR #molecular #biology

Also out this week: multiparameter #evolution training of #phage to target #Pseudomonas for improved cocktails in #phagetherapy. #publication in Nature Communications with Kunisch etal: nature.com/articles/s4146… #microbiology #bacteria

Putting #phage #antibiotic synergy into practice. Co-delivery formulation approach for #MRSA treatment in fracture-related infections . #publication in npj Journals with AO Foundation nature.com/articles/s4152… #FRI #AMR #clinic #microbiology #staphylococcus

And here's our new UZ Leuven standardized bench-to-bedside protocol to assess kinetics and dynamics of #Phagetherapy for #musculoskeletal #infections. #publication in Frontiers #Cellular and #infection #Microbiology frontiersin.org/journals/cellu… #PhageForce

Wonderful guest editing a special issue in Current Opinion in #Microbiology with the amazing FrunzkeLab, entitled: Host-Microbe Interactions: #viruses 2024. Check out the 12 amazing contributions and our #Tolkien inspired editorial : sciencedirect.com/special-issue/…

Tools, tools, tools Check out our #phage #protocols in Springer Publishing in #Methods in #Molecular #Biology ONT cappable seq #transcriptome Mapping: link.springer.com/protocol/10.10… CRISPR/Cas3 Based lytic phage #genome #Engineering : link.springer.com/protocol/10.10…

Thank you Karim & team for the fruitfull and efficient collaboration

Go beyond #genome #sequencing ! Giant #Pseudomonas #phage #transcription landscape reveals novel #sRNA & regulatory elements. Relevant to phage #biology & #microbiology #SyntheticBiology #research #Publication in Microbial Biotechnology (MBT) doi.org/10.1111/1751-7… European Research Council (ERC)

Engineering a phi15-based #expression system for stringent #gene expression in #Pseudomonas putida—led by Eveline-Marie Lammens, Daniel Volke in a nice collab between Nikel SEM Group & Rob Lavigne's team nature.com/articles/s4200…

linkedin.com/posts/rob-lavi…

Congrats to Kevin Minyoung Kim and Jessica Sacher, PhD on their review of phage therapy production and drug development. It was great working with Dr. Sabrina Green, PhD, Jean-Paul Pirnay, Rob Lavigne, Gina Suh and the rest of the team on this project jci.org/articles/view/…

Personalized or one-size-fits-all: the phage therapy field's favorite binary. Or is it a spectrum? Excited to share our new Journal of Clinical Investigation review, a team effort spanning Stanford University, Mayo Clinic, KU Leuven & QAMH, driven forward by the incredible Kevin Minyoung Kim! 🧵 /1

linkedin.com/posts/biotope-…