Happy to share our latest story revealing how type III CRISPR-Cas ancillary effectors tactically inhibit translation to combat phage infections: science.org/doi/10.1126/sc…. Here is a thread covering major points: (1/9)

Great work by former grad student @EvanASchwartz and postdoc Jack Bravo NaturalSciences @ UT Molecular Biosciences and Mohd Ahsan Giulia Palermo in Nature Communications! Couldn’t happen without long time collaborators Rob Fagerlund and Peter Fineran University of Otago. link.springer.com/10.1038/s41467…

Great to see this out! Always a great time working with the dream team David Taylor Peter Fineran Giulia Palermo Rob Fagerlund and my co-first authors @EvanASchwartz and Mohd Ahsan.

Cellular repair of DNA breaks enables editing of the human genome. Do human cells repair RNA breaks, and can we use it to edit transcriptomes? Our work with Anna Nemudraia and Wiedenheft Lab is now online in Science Magazine! #ScienceResearch science.org/doi/10.1126/sc…

A couple of delays, but finally managed to attend my induction as a new Fellow of the Royal Society of New Zealand Royal Society Te Apārangi Microbiology and Immunology Otago University of Otago Thanks to all the students, staff and collaborators who enable us to do fun research!

I'm so happy to share our SpRY-Cas9 story in its final form! Congratulations to first author Grace Hibshman - it was a great collaboration with a diverse team led by David Taylor, including Ilya Finkelstein and many others... 1/n rdcu.be/dGkLq

I am thrilled to share my latest work, out today in nature. This project started ~18 months ago as a blueprint for my own lab, which will start at ISTAustria in July, but not have been possible without the support of David Taylor & the whole team nature.com/articles/s4158…

🎉 Excited to share our latest paper in Cell Host & Microbe! Huge congrats to amazing co-first fabienne.benz & Sarah Camara (in my profile pic! 🥂) for pushing this work from start to finish! 🚀 1/5 🔗sciencedirect.com/science/articl…

Excited to see our work out now in Cell Host & Microbe ! 🤩 huge team effort, kudos to everyone involved, especially fabienne.benz & Rafa Pinilla-Redondo ! 🫶

@mfwhite2 was not wrong saying type III #CRISPR systems are “arguably more interesting”! Here we characterise Cas10s, second messengers and some new effectors in my first first-author postdoc paper in University of St Andrews, School of Biology🥳 Thanks @Skr_fi doi.org/10.1093/nar/gk…

In our new paper at Cell (Cell), we reveal secrets of how the third form of life, archaea, make energy. We uncover new lineages of hydrogen-using enzymes, both minimal and complex. These help archaea thrive in all sorts of extreme environments. sciencedirect.com/science/articl…

Couple of recent publications from our group!! 1) Awesome work from post-doc Will Jowsey showing how drug-resistance in Mtb alters tolerance to cell wall inhibitors! doi.org/10.1093/jacamr… (1/2)

👋🏻 I'm absolutely glee-ridden to finally see our study on the RNA- and DNA-binding anti-CRISPR repressor Aca2 published in nature. 🥳 This unassuming little helix–turn–helix protein packs quite the punch! 🧶👇🏻 rdcu.be/dNl45

Congrats Shaharn Cameron 🙌🙌🙌

If you're after some light reading to start your week, here's a short piece I wrote for The Conversation (The Conversation - Australia + New Zealand) on our recent anti-#CRISPR regulation work and its relevance for understanding #phage–host interactions: theconversation.com/viruses-can-wo…

I had a great time yesterday presenting my research on the type I-D CRISPR-Cas system at #BMH2024 for RNA technology day. Thank you to IUBMB and NZSBMB for your support!

Deadline Extension for Abstract Submissions Good news! The deadline for abstract submissions has been extended to Monday 28 October. This is your chance to showcase your research by submitting either an oral or poster presentation for CRISPR 2025. #crispr #crispr2025 #phage

I got hit by some rather sudden and extreme financial hardship so if anyone is in need of remote wetlab contract research, strictly BSL1, do let me know. Currently scrambling for gigs. Plant, Bacterial, Archaeal Bioeng Custom Lab Hardware Turn Key Genetic Design Please RT 💚