#ICYMI: NCATS partnered with FAES again to offer MEDI501: Principles of #TranslationalScience, a 7-week online course, from Aug. 30–Oct. 15, 2021. Space is limited, so register today: go.usa.gov/xH9rC

Bob's Med Chem Fact of the Day Drugs have unique target product profiles (TPP), with different safety and PK needs. Thus, don't blindly use the line "this functional group is in approved drugs" in discussions, without understanding of respective TPPs, synthetic challenges, etc.

Who doesn't love a beautiful cover? Congratulations to Marcus Fischer TheFischerLab, Shanshan Y. C. Bradford, and Maddie Rice Maddie Rice! Don't miss the article bit.ly/Fischer_Media and the manuscript rsc.li/2WLrAbk St. Jude Research

Please save the date for the Advances in Antibacterial Discovery virtual mini-symposium. It is free to attend and I am delighted with the line-up of speakers. It should be a great day. bit.ly/3yNSz3b

We have a great new lab research website; enjoy. stjude.org/research/labs/…

Big day in the Lee lab, 5000th molecule advances to biological testing and is celebrated with ice cream cake. I want to thank the hard work of all those who have synthesized and tested these unique molecules over the past twenty years.

Organic acidemias are a group of inherited metabolic disorders with significant morbidity and mortality. New data published today by @stjuderesearch in Science Translational Medicine may support the potential for our investigational therapy to help these patients in need. bit.ly/3hxVQy8

Please join us for the Advances in Antibacterial Discovery symposium on Dec 3. The conference is hosted by @richardleelab and features a wonderful speaker lineup. Register here: bit.ly/3yNSz3b @stjuderesearch

LipE rocks. Happy to report the details on how our LipE driven hit to lead program for PanK produced our initial preclinical lead. doi.org/10.1016/j.bmc.…

pubs.acs.org/doi/10.1021/ac…

New paper about a surprisingly difficult TB drug target to ligand with non-peptides bit.ly/3owDZvg

Congrats to Stephanie Reeve @reeve_steph for winning the best presentation award at the St Jude Chemical Biology Therapeutics dept retreat and receiving the much-coveted CBT belt. I am lucky to have such a talented postdoc in my lab. @stjuderesearch @ansarilab @richardleelab

This…

.Volodymyr Zelenskyy / Володимир Зеленський's tv address to the Russian (!) people might be the most moving speech that I've ever seen in my entire life. The whole world needs to see, understand and share this crucial Ukrainian message. #StandWithUkraine #Ukraine #Україна #Russia #Россия

Proud to hear my former trainee Julian Hurdle was promoted to full professor at Texas A&M Health Science Center. Congrats Julian, you are an outstanding scientist.bit.ly/3IjDBaZ #blackinchem

One of the more fun activities available in Memphis, a great night out for the lab

Looking forward to speaking on new approaches to antibiotic discovery at the GARDP webinar. revive.gardp.org/new-approaches… Global Antibiotic R&D Partnership (GARDP) St. Jude Research

St. Jude is built on a strong foundation of collaborative interactions spanning many disciplines, including biomedical sciences, global child health and clinical investigations. Learn more. ow.ly/FUfa50IPeER

Another development milestone for our program to potentially treat coenzyme-A (CoA) deficiencies! We recently dosed the first patient in our PA/MMA clinical trial. $BBIO bit.ly/3PxmJQO

Holy cow! Open call for a Researcher position (MSc or PhD, no post-doc experience needed). This will person will be a part of the Pediatric Dependencies Project - a collaboration between Broad Institute, Dana-Farber/Boston Children's and St. Jude Research! Cool, right? talent.stjude.org/careers/jobs/1…