Looks like Joan is a clue in the WashPo crossword puzzle today! 🤓 washingtonpost.com/crosswords/dai…

The business model of Hindenburg Research is fascinating: They produce some of the best, in-depth investigative journalism, aiming to expose shady actors, which are *always* publicly traded companies. They do this for free: as they short the stock when they publish the report.

Please read this:

Nouveau labo! Je cherche des étudiant(e)s gradué(e)s voulant travailler dans le domaine de l'épissage de l'ARN en #cancer et #immunologie. New lab! I'm looking for grad students interested in #RNAsplicing in #cancer and #immunology mqvlab.com Jr RNA Scientists

📢 Paper alert! Are you interested in #RNA Alternative Polyadenlyation (APA)? Maybe you quantify APA from RNA-Seq? But there are so many methods for that - which method should you be using?? 🤔…1/n

Can current genomic sequence-to-expression models explain expression variation across individuals based on their personal genome? In the Ioannidis Lab at UC Berkeley, we evaluated 4 state-of-the-art models for this (Enformer, Basenji2, ExPecto, Xpresso) biorxiv.org/content/10.110…

Summary of current bike access to Penn Medicine research buildings. This is the worst of Philly bike-unfriendliness - Penn could do much more to use its bully pulpit and resources to make its campus accessible by bike, which would help it attract and retain employees.

Angiotensinogen RNA interference to lower BP. The new era of RNA therapeutics might be here. nejm.org/doi/full/10.10…

Please join us for an exciting #RNA Day (AUG 1) celebration (with BEER!) co-hosted by RBI, Colorado RNA Club, and Project Bridge Colorado. All are welcome! Come learn about RNA Biology in simple, everyday language Kyle Clark and 9NEWS Denver watchers!

SOO excited to see the final LRGASP preprint out! The largest benchmark of #longreads for transcriptomics. A must-read if you plan on doing lrRNA-seq. Thanks to so many for the huge work Francisco Pardo-Palacios Brooks Lab Mark Diekhans Gloria Sheynkman Ali Mortazavi biorxiv.org/content/10.110…

Happy RNA Day!

Thank you to Biotechnology and Biological Sciences Research for funding our proposal on the role of human-specific TEs in human neurodevelopment. We will be soon advertising a 3-year postdoc position. If you are interested feel free to email. The project will involve iPSC/organoids/scRNA-seq/CRISPR and more! Please RT

Excited to announce our latest preprint! Check out this work from visiting scientist Lindsay Romo and postdoc Scott Findlay, leveraging our knowledge of RNA regulatory features to interpret and prioritize 3'UTR variants in humans 🧬🤔🎉biorxiv.org/cgi/content/sh…

In new work, @LambdaMoses et al. introduce the Voyager platform for spatial and non-spatial 'omics analysis: 🚴‍♀️ Builds on the geospatial statistics tradition 🚴‍♀️ Addresses discordance between Seurat & Scanpy 🚴‍♀️ Engineered in R (Bioconductor) & Python biorxiv.org/content/10.110… 1/🧵

We identified a mechanism by which the homeostasis of class of proteins with similar low complexity domains (LCDs) is collectively regulated – ‘interstasis’. Interstasis operates at the level of the RNA that encodes those LCDs by exploiting the structure of the genetic code.

Great to see this paper published! Xiaoting Li and Harmen Bussemaker developed a really creative way to robustly quantify TF activity, which we then used as a phenotype in GWAS.

I´m thrilled to see our #LRGASP paper published in Nature Methods today. This is the work of many to benchmark long-read methods for transcriptomics, and a must-read paper for those using lrRNA-seq. Special thnks to Francisco Pardo-Palacios and Brooks Lab (1/6) rdcu.be/dJ9ev

Genetic evidence halves the odds of early clinical trial stoppage 🧬💊 Published today in Nature Genetics, Olesya Razuvayevskaya trained a machine learning classifier to analyse the free-text reasons explaining why 28,842 clinical trials stopped 3 key points: nature.com/articles/s4158…

You want to know who won? Find out who refuses to do a 2nd debate.

Come join us at rm 104 at 12 noon tomorrow (Friday) to enjoy the finest sandwiches that Colorado Convention Center has to offer, AND to hear about the world's largest cohort for genomics research - Our Future Health - and how it can enable your research #ASHG2024 Our Future Health