🫀 Does Alirocumab affect #platelet function in patients with #MI ? ⤵️

📌 Among pts. receiving DAPT in the PACMAN-AMI Trial, #Alirocumab had no significant effect on platelet reactivity

In TH current issue 👉 thieme-connect.de/products/ejour…

#PCSK9 #CardioTwitter Lorenz Räber, MD PhD

Secondary stroke prevention in people with AF - published ⁦The Lancet Neurology⁩! fantastic team work valeria caso⁩ ⁦Lorenz Räber, MD PhD⁩ ⁦Urs Martin Fischer⁩ ⁦UCL Stroke Research⁩ ⁦Ashkan Shoamanesh⁩ ⁦European Stroke Org⁩ ⁦Stroke Research Center Bern⁩ authors.elsevier.com/a/1inIG5FFzL0D…

Pretreatment with P2Y12 inhibitors in #STEMI - insights from the Bern-PCI Registry

This study sought to compare outcomes 📈📉 between patients presenting with STEMI before & after the recent ESC guidelines for the management of ACS recommendation against pre-treatment with…

In the Bern PCI registry, we evaluated the impact of the recent downgrade of P2Y12i preloading in STEMI (ESC Guidelines) as we stopped preloading in 2018. No preloading was not associated with increased hazards in ischemic outcomes 30days. Read jacc.org/doi/10.1016/j.… European Society of Cardiology

sbaer Lorenz Räber, MD PhD and colleagues show that in ACS patients with multi-vessel disease undergoing planned staged PCI, non-culprit quantitative flow ratio did not identify patients benefiting from earlier intervention. #AHAJournals ahajrnls.org/3HeeJTe

Only disappointingly little legacy effect following overweight medication cessation. (tirzepatide) How to predict longterm adherence to an expensive injectable? Overweight is a disease, not just bad habit. #weightloss European Society of Cardiology SwissCardio

How to handle ⚡️🧠ischemic #stroke despite 💊🩸oral #anticoagulation in patients with ❤️🎶🎵 🎶 #AFib ?

Latest summary by Roberto Galea David Seiffge Lorenz Räber, MD PhD

mdpi.com/2077-0383/12/1…

Dipeptidyl peptidase 3 in ACS

👉🏻 Novel marker of #cardiogenicshock
👉🏻 Predicts mortality
👉🏻 Linked to MI size
👉🏻 Therapeutic target

CardioTomLuscher Lorenz Räber, MD PhD Francesco Bruno Marco Roffi David Niederseer Ste_MNS
SwissCardio SwissCOT Universität Zürich Center for Molecular Cardiology European Society of Cardiology Journals #CardioTwitter

#ESC #fasttrack Concomitant Coronary Atheroma Regression&Stabilization in Response to Lipid-Lowering Therapy | JACC jacc.org/doi/10.1016/j.…
Congratulations to Flavio Biccirè for his presentation European Society of Cardiology and simultaneous publication in JACC Journals PCRonline 🫀 Cardiovascular Research Cluster (CVRC) Universität Bern

Stent failure management:

Discover the optimal use of intracoronary ⭕️ imaging and learn more about the differential role of IVUS and OCT imaging in stent failure in this session replay 📺

Lorenz Räber, MD PhD Shereen AlShaikh Salvatore Brugaletta

pcronline.com/Cases-resource…

#CardioTwitter

Balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension is very efficacious treatment option. Read the just released consensus statement of the ESC working group on pulmonary circulation&right ventricular function academic.oup.com/eurheartj/arti…

Join experts Ph.Gabriel Steg , Dr. Deepak L. Bhatt, Lorenz Räber, MD PhD, Lale Tokgozoglu and learn the latest data 📊on lipid-lowering strategies in the post-ACS period
📅 26 August, 2023
📍Amsterdam,The Netherlands
🔗 esc365.escardio.org/ESC-Congress/s…

#cardiology #ESCcongress

Two Investigator Initiated Clinical Trial Grants from Schweizerischer Nationalfonds (SNF) for the Medical Faculty of Universität Bern. 🥂Congratulations to Reto Auer, Lorenz Räber, MD PhD, and David Seiffge for this big success. Here is a summary of their projects addressing important unmet needs: medizin.unibe.ch/research/index…

In PACMAN-AMI, the PCSK9i alirocumab led to significant regression of non-obstructive lesions at 1 year compared to placebo on top of rosuvastatin. New research shows that this effect did not translate into significant improvement in coronary physiology. eurointervention.pcronline.com/article/impact…

Drs. Roberto Galea, Lorenz Räber, MD PhD et al find significant improvement in procedural success with preprocedural CT to plan LAAC in a post-hoc analysis of the SWISS-APERO Trial. bit.ly/3JkA2nj

#JACCINT #cvLAAoccluder #CardioTwitter Christoph Gräni Marco Valgimigli

Very nice session on breakthrough stroke despite anticoagulation at #ESOC2023
This very common clinical problem needs our attention in clinics and research🧠🫀❤️💊
Sashi Perera, MD Edip Gurol Luciano Sposato 🇦🇷🇨🇦 David Seiffge Alex Polymeris Lorenz Räber, MD PhD

Linking blood pressure and inflammation in #ACS
👉systemic inflammation associates inversely with systolic BP
👉>100mmHg = ⬆️ #cardiogenic #shock risk
👉if ⬆️systemic inflammation = ⬆️ MACE risk
Simon Kraler Florian Wenzl Lorenz Räber, MD PhD CardioTomLuscher European Society of Cardiology University of Zurich European Society of Cardiology Journals

Breaking news: UBS has agreed to buy Credit Suisse after increasing its offer to more than $2bn
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