Cancer Chemotherapy Cancer Cell

Glad to share our study in npj Precision Oncology nature.com/articles/s4169…, where we cross-compared transcriptomes and immune infiltration in ILC tumors, building on work by Sayali Onkar, PhD (nature.com/articles/s4301…). Our findings reveal a proliferative subtype linked to increased

Congratulations to Steffi Oesterreich, PhD, this year’s recipient of the AACR Distinguished Lectureship in Breast Cancer Research. Dr. Oesterreich will present her award lecture at #SABCS24 on December 12. bit.ly/3YTGkBg UPMC Hillman Cancer Center SABCS

There are only two days left to apply to #FLARE2025 (bit.ly/2N5iKxV) and #ExCEL2025 (bit.ly/3waSFCh)! These prestigious leadership programs provide a unique opportunity to develop professional skills, connect with experienced mentors, and advance your career in

I am immensely proud of Steffi for receiving this award for her breast cancer research, particularly #lobular. She has dedicated her career to this goal and paid special attention to trainees and the involvement of advocates. See her talk at SABCS #BCSM

I am incredibly grateful for this recognition! To be listed among scientists who have made indelible marks of pioneering advancements --- what a humbling experience!

We’re thrilled to share our Nature Methods review on #CellPainting — your go-to resource for mastering Cell Painting! From MOA and toxicity prediction to contributing to candidate drugs in clinical trials, we’ve distilled 10 years of insights! Free link: rdcu.be/d2vHH

🎯 Read the new amazing research from the labs of Gordon Hager & Frank Dequiedt lead by Grégory Fettweis Kaustubh Wagh #DianaStavreva Alba Jiménez-Panizo, PhD & rest of collaborators. Always a great pleasure working with these team of awesome scientists 🪐✨️

Our work on metabolism of quiescent cells! A bit of a new area for us in collaboration with the Buckanovich lab

We got another grant rejection today but I remain unfazed. I know where I started and the impact I’ve had already, and I know the impact I will have going forward. If I required others to see my potential and my vision to forge ahead, I’d have stopped long ago.

This is such an unacceptable response for an NIH PD to give to a trainee. For the record she did read the notices and discuss with her mentor (me), and I recommended she reach out and ask. Wonder why talented young people are leaving academia? This is why NIH 😑

Always good to see TBIO Alumni out & about irl! 🎉 Great running into you Apsra Nasir (front, TBIO MS & TBIO PhD), Dr Aileen Fernandez Fernandez (she/her/hers) (left, UDC/LCCC MS & TBIO PhD), & Jamie Holloway, PhD (right, TBIO PhD) at SABCS 2024

Just Published to close off the year! Our latest work explores the dynamic interplay between ER and HER2 in breast cancer, revealing how treatment drives receptor discordance and impacts clinical outcomes. Beaumont RCSI Cancer Centre RCSI RCSI School of Pharmacy and Biomolecular Sciences onlinelibrary.wiley.com/doi/10.1002/ca…

I am excited to share our work in Journal of Molecular Biology, which is our 7th publication on #nuclearreceptors for the 2024 calendar year! Please read on for a summary of all 7 publications from our lab this year, as well as links to the papers.

The LEANORA study: Understanding the pharmacokinetics and pharmacogenomics of ribociclib in black women Max Smith Sandra communities.springernature.com/posts/the-lean…

Super excited to join this program with an amazing legacy of current and past Fellows! I am so thankful for those who supported my application, and I look forward to making the most of this wonderful opportunity and engaging with the vibrant and diverse Keystone community!

Woohoo! Our latest preprint, from Madhura Nijsure Nijsure, is out today bioRxiv! YAP regulates periosteal expansion in fracture repair. biorxiv.org/content/10.110…

🎯 Thrilled to share our new paper in collaboration lead by Alireza Mashaghi and Team on the Androgen Receptor with a key role in the pathophysiology of spinal and bulbar muscular atrophy (SBMA, Kennedy's disease) due to polyglutamine expansions 🧩 Alba Jiménez-Panizo, PhD Andrea Alegre Martí

Do you use Hallmark_Estrogen_Response_Early/Late signatures from MSigDB? Then try out more comprehensive signatures such as ones we generated from gene expression changes across 66 RNA-seq and 80 microarray experiments e.g. LI_ESTROGENE_META_E2_RESPONSE_UP gsea-msigdb.org/gsea/msigdb/hu…

Latest journey in #prostatecancer cell plasticity. Team effort Christopher Sweeney, MBBS Katherine Morel Beatriz Work stems from previous Christopher Sweeney, MBBS investigations in NFkB regulation by tristetraprolin (TTP; gene ZFP36), and generation of the NFkBi dimethylaminoparthenolide (DMAPT)