Online now! ✨RESEARCH: Pingze Zhang et al identify Syntaxin-13 as a conserved effector of rapamycin’s longevity effects, operating in the Drosophila fat body to regulate lysosomes and inflammation in a sex-specific manner MPI for Biology of Ageing doi.org/10.1038/s43587… rdcu.be/dzYgY

Big thank you Cathy Slack and @ScotsFriction for the invaluable efforts in this project. Couldn’t have done it without you both and the other trailblazers☺️

Ageing research news from our friends MPI for Biology of Ageing and led by our Chair of the Board Prof. Dame Linda Partridge: Anti-ageing drug rapamycin improves immune function through endolysosomes age.mpg.de/392233/240228_…

Big paper alert: TNIK inhibitor designed using generative AI targets fibrosis in preclinical and clinical trials nature.com/articles/s4158…

We are hiring TWO research assistants to join the lab. 1)Molecular biology of aging postdocs.yale.edu/postgraduate-p… and 2)lipid biology and mass spectrometry postdocs.yale.edu/postgraduate-p… Interested in aging, stem cells, lipids and mass spec? Please reach out!☺️

Very cool - rejuvenation of the immune system! nature.com/articles/s4158…

We Made the Cover! 📘✨ I'm incredibly excited to share with you that the illustration I made for Zhang et al. paper on mTOR, inflammaging and longevity has been featured on the cover of the Nature Aging April issue.

A combination of intermittent Rapamycin and Trametinib leads to an additive effect on lifespan extension in hybrid mice. Great work from Gkioni and colleagues at the Partridge lab! biorxiv.org/content/10.110…

Dear Network: I am looking for an expert microbiologist and expert synthetic biologist for a. scientist adventure. Please DM me.

Fascinating paper on evolutionarily conserved mechanisms of S6K in regulating inflammaging, echoing our previous findings nature.com/articles/s4358…. Curious if fibroblasts or macrophages play a role in inflammation in older mice? Congrats to all the authors! 👏

Never regret joining the CSHL Mechanisms of Aging Conference! It was such a thrill to engage with pioneers in the field. Plus, (post-graduation) presenting my PhD work right after my supervisor's keynote speech? An unforgettable experience! 😜🍻 #cshlaging #aging

📢 I am so incredibly happy and proud about this one! 🔟+ years in the making, 2,5 years since first submission, 1⃣ year since we posted it bioRxiv, it finally found it’s home Nature Cell Biology! Open access 👇 nature.com/articles/s4155… Detailed 🧵down below ⏬

Huge publication in nature by Calico disentangling the contribution of genetic diversity to dietary interventions! Treasure chest of results - like the observation that the biggest determinant of lifespan extension are immune- but not metabolism-related shorturl.at/vASeP

🚨Join an exceptional meeting this October to learn about the most novel, cutting-edge strategies for studying the biology of aging and combating age-related diseases. 🚀 With an extraordinary lineup, this is an event you absolutely won’t want to miss!! 👉tinyurl.com/3yveywwv

We have a 4-year postdoc position open in our Research Unit on proteostasis! The project explores inter-tissue regulation using advanced proteomics approaches. Collaborative & interdisciplinary environment. More details & application here: jobs-uk-koeln.onlyfy.jobs/job/pktg6ivjss…

🗞️Our May issue is live!📷 This month, we're featuring work on planarians and rejuvenation, how ancient viruses factor into mammalian reproduction, mitochondrial biology in aging, age-related hearing loss, and much more. Read it all here 👇nature.com/nataging/volum…

It's an amazing event! Thanks everyone for making it happening!!! Yale Center for Research on Aging (Y-Age) Vishwa Deep Dixit