📰 Article Review: Molecular Portraits of Human Breast Tumors ➡️2000 article by Perou et al 🧬Gene expression profiling: 65 breast tumors in 42 people 🥅To create system in classifying breast tumors based on gene profile 1️⃣ ER +, basal-like 2️⃣ ER+, luminal-like 3️⃣ HER2+

sometimes #GUpath prostate bx with inflammation can correlate with imaging abnormalities (high PIRADS) & worth mentioning... but when you do, just be descriptive ("prostatic tissue with acute/chronic inflammation") 🚫signout as "acute prostatitis" ⏬

🧬 Peutz-Jeghers Syndrome 🩺Mucocutaneous Pigmentation; Polyp (esp in Small Bowel) 🔬Polyps may 👀 like sporadic prolapse polyp 🩺 May present w intussusception 🧬Germline STK11 ⬆️ Risk Cancers: Breast, Colon, Gastric, Pancreatic ⬆️Risk Benign Tumors: SCTAT, Sertoli Cell Tumor

📰Article Review on Incidental Findings in Colorectal Polyps ⚠️ Important to know so don't misdiagnose as high grade dysplasia or cancer 1️⃣ Squamous Metaplasia 2️⃣ Signet-ring cell-like lesions (2º sloughed epithelium) 3️⃣ Clear cell change 4️⃣ Neuroendocrine differentiation #pathx