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A humanized IL-2 mutein expands Tregs and prolongs transplant survival in preclinical models jci.org/articles/view/… Leonardo V. Riella

Since first kidney transplant >50 years ago, little has changed in the approach to prevent rejection after transplant. Excited to share our work changing the paradigm by expanding Tregs& allowing immunosuppression reduction jci.org/articles/view/… View details 👇 Mass General Transplant

New paper from Leonardo V. Riella lab showing the effect of a new engineered IL-2 in the prolongation of graft survival. Congrats Orhan Efe and team for this great work!

A humanized IL-2 mutein expands Tregs and prolongs transplant survival in preclinical models: buff.ly/4a1M9Rc Leonardo V. Riella Mass General Kidneys #Immunology #Transplantation

#Commentary: Tipping the balance toward transplantation tolerance: in vivo therapy using a mutated IL-2: buff.ly/3V9GAMv UPMC Related article: buff.ly/4a1M9Rc

Our review of membranous nephropathy is out. We focused on most current understanding and management as well as evolving therapeutics. indianjnephrol.org/an-updated-rev… Indian Journal of Nephrology Paolo Nikolai So Urmila Anandh Edgar V. Lerma 🇵🇭 Nasim Wiegley, MD, FASN GlomCon Mass General Kidneys The Brigham Nephrology @harvardmed

Our take on a promising strategy to prolong allograft survival 👇🏽👇🏽 Mass General Transplant Leonardo V. Riella Orhan Efe AST Community of Transplant Scientists

Please donate if you can. The southernmost state of Brazil is underwater. Many members of the Leonardo V. Riella lab are from this place, and we have family members and dear friends who lost everything 😢 Rodrigo Benedetti Gassen Karina Lima Isa Lape

Congratulations to our amazing fellows! Grateful and humbled for the recognition and being part of your journey🙏🏻 Mass General Kidneys The Brigham Nephrology @harvardmed