Very excited to share two papers published today in Cell describing stem cell plasticity in CRC. (1/22) cell.com/cell/fulltext/… cell.com/cell/fulltext/…

Pleased to share our new collaborative study (w/ the Vennetilab), led by Nneka Mbah #OpenAccess Nature Communications Check it out 👇🏼 and/or follow along for the #tweetorial (1/11) nature.com/articles/s4146…

Great read! 🧠 nature.com/immersive/d415…

🎉Excited to present our latest work out today nature 1.What gives a leukemia its phenotype – the oncogenic driver or the differentiation stage of the cell-of-origin? 2.Why do RAS mutations always happen late in AML? 3.Who will relapse after VEN? nature.com/articles/s4158…

Transcriptome-wide splicing network reveals specialized regulatory functions of the core spliceosome doi.org/10.1126/scienc…

A multiplex single-cell RNA-Seq pharmacotranscriptomics pipeline for drug discovery nature.com/articles/s4158…

A CRISPR screen targeting RNA identifies essential lncRNAs in human cells, revealing lncRNAs whose expression correlates with the survival of tumors, identifying new biomarkers and potential targets for therapeutics cell.com/cell/fulltext/… #NBThighlight

We are looking for a student in bioinformatics to work on an exciting project bridging embryonic development and childhood brain cancers. Please RT!!

You can find me on BlueSky at olivier-saulnier.bsky.social I'm excited to participate in a new safe place for science aficionados!

REVIEW: Approaches to investigate tissue-resident innate lymphocytes metabolism at the single-cell level nature.com/articles/s4146… @DavidFinlayTCD

Transposable element exonization generates a reservoir of evolving and functional protein isoforms cell.com/cell/fulltext/…

Molecular and cellular dynamics of the developing human neocortex nature.com/articles/s4158…

Happy to share our update to LeafCutter, which allows the study of unproductive splicing from short-read RNA-seq. We report findings from analysis of 3 large datasets (GTEx, multi-tissue development in 7 species, Alzheimer brains from AD FunGen consortium). See thread by Carlos.

Excited to share our latest (and first from the lab) preprint where we investigated the molecular mechanisms that drive Nestin-expression progenitor differentiation in the developing cerebellum. 🧠 biorxiv.org/content/10.110…

1/ Truly excited to share our new study that I had to privilege to co-lead during my PhD alongside great friends and collaborators Masashi Nomura, Kevin C. Johnson and Luciano Garofano, which was published Nature Genetics! nature.com/articles/s4158…

Super excited to share our latest work on #RNA liquid biopsy via Oxford Nanopore sequencing for novel biomarker discovery and #cancer early detection! biorxiv.org/content/10.110… Thank you American Cancer Society ACS Research for supporting our research!