Ive not been super public about this, but in less than 200 days: we've gotten significantly returned quality of life to a long-term Parkinson's patient and $8 bottles of sublingual thiamine tablets (L-dopa had already stopped working for him. It only "works" about 5 years)

How the brain talks to the immune system This diagram shows the inflammatory reflex - a neural circuit where the brain regulates inflammation through the vagus nerve. It’s how psychological stress, inflammation, and immune activity stay linked. 1️⃣ The signal starts in the brain

Where neurotransmitters and micronutrients team up in your body Neurotransmitters are chemicals that help your brain and nerves communicate, and they rely on micronutrients to be made. This chart shows how amino acids like L-phenylalanine and L-tryptophan turn into key

3 types of hunger explained "simply" Hunger isn’t just about an empty stomach. Your brain receives signals from body composition, hormones, emotions, and even gut microbes. Here’s how the three major types work: 1️⃣ Homeostatic Hunger (Energy Balance Hunger) This is your body’s

How Coffee Roasting Changes Chlorogenic Acids (and Other Antioxidants) Coffee beans are packed with chlorogenic acids - plant compounds that help regulate blood sugar, protect blood vessels, and act as antioxidants. Roasting changes how much of these (and other polyphenols) end

A guide to understanding how Omega-3s affect muscle Omega-3 fatty acids (EPA and DHA), found in foods like fish, seeds, and certain oils, don’t just support heart and brain health. They also shape how your muscles use energy and build protein. 1️⃣ Omega-3s Start with Diet You

Best time to take your supplements 1. Magnesium- 1 hour before bed. 2. Vitamin D- with your breakfast. 3. Calcium- Split between AM/PM. 4. Probiotics- On an empty stomach. 5. Omega 3- with fat containing meal. 6. B complex- early in the morning. 7. Vitamin E- right after

Untitled Sue Ieraci For that very reason, in fact 1. Dopaminergic neurons in the SN display functional thiamine deficiency (inhibition/blockade) of thiamine dependent enzymes. High dose thiamine reactivates them 2. Thiamine is inherently pro-dopaminergic. Supplementation evokes dopamine release in

st0nkb0t11k Untitled Sue Ieraci I prefer to use the term "effective dose" instead High dose could range anywhere from 10-1000x the RDA. However, the EFFECTIVE dose is usually in the 200mg-1000mg range (depending on form)

Symptoms Of MINERALS Deficiencies ZINC - Acne, Hair thinning, Allergies, Low immunity, Hormonal imbalances, Low testosterone, Low libido IRON - Chest pain, Fatigue, Hair loss, Headaches, Cold hands & feet, Shortness of breath SELENIUM - Hair loss, Slow metabolism, Thyroid

Vitamin D - built in 3 organs Here’s the shortcut to how sunlight becomes a hormone in 7️⃣ steps: 1️⃣ Sunlight Sparks It UVB converts 7-dehydrocholesterol in skin into Vitamin D₃. 💡 Low sun, sunscreen, darker skin → less D₃ formed. 2️⃣ Or You Eat It Fatty fish, eggs,

Amino acids and the brain: how protein shapes cognition Amino acids aren’t just for muscle; they’re the raw materials for neurotransmitters, brain energy, and communication between neurons. Every thought, mood, and memory depends on them. 1️⃣ The Building Blocks of Brain

3 types of hunger explained "simply" Hunger isn’t just about an empty stomach. Your brain receives signals from body composition, hormones, emotions, and even gut microbes. Here’s how the three major types work: 1️⃣ Homeostatic Hunger (Energy Balance Hunger) This is your body’s

Vitamins and brain health how micronutrients power the nervous system Your brain is the most energy-hungry organ in the body. Every thought, movement, and emotion depends on a continuous supply of nutrients that maintain energy production, neuronal structure, and

1) Propionyl-L-Carnitine This specialised amino acid improves blood flow to your damaged gut tissues. Healing happens 3x faster with proper circulation. It protects mitochondrial function and reduces inflammatory cytokines. Game-changer for mucosal healing.

2) Ultimate GI Repair (Zinc Carnosine / BPC-157) Bioactive peptides and precision nutrients help maintain gut lining integrity, digestive function, and barrier resilience." Reinforces the gut barrier, supports tissue renewal, modulates the immune environment. S-tier

Core additions: - Coconut oil - Celery/greens - Curcumin - Magnesium - Cod liver oil These are all foundational. Don't skip them.

Metabolism of vitamin D

Your hormones run your entire life, and most people have no idea how many of them exist or what they do. Mood. Energy. Metabolism. Strength. Sleep. Stress. Fertility. Hunger. Recovery. There’s a hormone for nearly every single function your body performs, and this chart shows

This is how neurons talk. And once you understand this, a lot of human behavior suddenly makes more sense. GABA Your brain’s main calming signal. Helps keep neurons from firing out of control. The reason relaxation is even possible. Glutamate The primary excitatory signal.