Nikhil Bassi, MD (@nikhilbassimd) 's Twitter Profile
Nikhil Bassi, MD

@nikhilbassimd

Cardiologist working at Hoag Hospital. Proud UCLA Cardiology Fellow grad #BruinHearts. #UCIMR grad. Former Northwestern Wildcat.

ID: 984299103583645696

calendar_today12-04-2018 05:16:08

500 Tweet

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JACC Journals (@jaccjournals) 's Twitter Profile Photo

In a new study from #MESA, #CAC distribution (number & specific arteries) was assoc w/ risk & improved risk prediction independent of traditional risk factors & plaque burden assessed by CAC volume & density. jacc.org/doi/10.1016/j.… #JACCIMG Harpreet Bhatia Tara Shrout Allen

In a new study from #MESA, #CAC distribution (number &amp; specific arteries) was assoc w/ risk &amp; improved risk prediction independent of traditional risk factors &amp; plaque burden assessed by CAC volume &amp; density. jacc.org/doi/10.1016/j.…  #JACCIMG <a href="/hsbhatia/">Harpreet Bhatia</a> <a href="/TaraAllenMD/">Tara Shrout Allen</a>
American College of Cardiology (@accintouch) 's Twitter Profile Photo

Learn about the unique role of Lp(a) as a genetic determinant for #ASCVD risk & the importance of testing for Lp(a) levels to better understand your patients’ cardiovascular health w/ ACC's online course. ⬇️ More: bit.ly/3WmPipH #LpaAwarenessDay #KnowLpa #ACCEd

Learn about the unique role of Lp(a) as a genetic determinant for #ASCVD risk &amp; the importance of testing for Lp(a) levels to better understand your patients’ cardiovascular health w/ ACC's online course. ⬇️

More: bit.ly/3WmPipH

#LpaAwarenessDay #KnowLpa #ACCEd
David Winchester @drdavemd.bsky.social (@drdavemd) 's Twitter Profile Photo

From the ISCHEMIA trial: Patients with CCD who achieve risk factor goals of care (BP, LDL, Antiplt, Smoking), have 50% lower risk of death @ 5 yrs than those who achieve none. JACC Journals jacc.org/doi/10.1016/j.…

From the ISCHEMIA trial: Patients with CCD who achieve risk factor goals of care (BP, LDL, Antiplt, Smoking), have 50% lower risk of death @ 5 yrs than those who achieve none. <a href="/JACCJournals/">JACC Journals</a> jacc.org/doi/10.1016/j.…
JACC Journals (@jaccjournals) 's Twitter Profile Photo

Bioprosthetic vs Mechanical #AorticValve Replacement: The debate rages on! 🏥 This new study suggests mechanical may be the way to go for younger patients. Where do you stand? 🤔 🔗 Full #JACC study: jacc.org/doi/10.1016/j.…

Bioprosthetic vs Mechanical #AorticValve Replacement: The debate rages on! 🏥 This new study suggests mechanical may be the way to go for younger patients. Where do you stand? 🤔

🔗 Full #JACC study: jacc.org/doi/10.1016/j.…
JACC Journals (@jaccjournals) 's Twitter Profile Photo

#JACCIMG prospective same-day #EchoFirst & #whyCMR study of aortic regurgitation: American Society of Echocardiography guidelines perform well to find significant AR; a simpler approach using vena contracta & LV volumes was also reliable. jacc.org/doi/10.1016/j.… Maan Malahfji WilliamZoghbi #vhdAR

#JACCIMG prospective same-day #EchoFirst &amp; #whyCMR study of aortic regurgitation: <a href="/ASE360/">American Society of Echocardiography</a> guidelines perform well to find significant AR; a simpler approach using vena contracta &amp; LV volumes was also reliable. jacc.org/doi/10.1016/j.…

<a href="/MaanMalahfji/">Maan Malahfji</a> <a href="/WilliamZoghbi/">WilliamZoghbi</a> #vhdAR
JACC Journals (@jaccjournals) 's Twitter Profile Photo

Ever wonder why some aortic dissections/sinus ruptures result in a connection to the RV? See how the anatomy makes this happen—insights you don’t want to miss! 🔬 🔗 jacc.org/doi/10.1016/j.… Kalyanam Shivkumar MD PhD #JACC

Ever wonder why some aortic dissections/sinus ruptures result in a connection to the RV? See how the anatomy makes this happen—insights you don’t want to miss! 🔬  

🔗 jacc.org/doi/10.1016/j.… <a href="/shivkumarmd/">Kalyanam Shivkumar MD PhD</a> #JACC
Circulation (@circaha) 's Twitter Profile Photo

After ACS on high-intensity statins, LDL-C, hs-CRP & Lp(a) independently predict future CV events. For Lp(a) & hs-CRP, risk starts at low levels. @VeraBittner2 @DLBhattMD Harvey White Robert Harrington Ph.Gabriel Steg ahajournals.org/doi/full/10.11…

After ACS on high-intensity statins, LDL-C, hs-CRP &amp; Lp(a) independently predict future CV events. For Lp(a) &amp; hs-CRP, risk starts at low levels. @VeraBittner2 @DLBhattMD <a href="/W66588221White/">Harvey White</a> <a href="/HeartBobH/">Robert Harrington</a> <a href="/gabrielsteg/">Ph.Gabriel Steg</a> ahajournals.org/doi/full/10.11…
Nikhil Bassi, MD (@nikhilbassimd) 's Twitter Profile Photo

Looking forward to attending Dr. Itchhaporia’s Health Tech Horizons course. Should be a great opportunity for learning and networking!

Muthu Vaduganathan (@mvaduganathan) 's Twitter Profile Photo

Intriguing new data out in JACC Journals in time for #HeartFailure2025 from ATTRibuteCM Stabilization of TTR (prealbumin) leads to immediate & sustained rise in TTR levels Degree of rise identifies those likely to derive mortality protection from TTR stabilizers #MedIQHF2025

Intriguing new data out in <a href="/JACCJournals/">JACC Journals</a> in time for #HeartFailure2025 from ATTRibuteCM

Stabilization of TTR (prealbumin) leads to immediate &amp; sustained rise in TTR levels  

Degree of rise identifies those likely to derive mortality protection from TTR stabilizers

#MedIQHF2025
JACC Journals (@jaccjournals) 's Twitter Profile Photo

Visualize the beauty of the heart 🫀: This left anterior oblique view shows septal perforators like you’ve never seen them. The art of precision lives here 🎨 jacc.org/doi/10.1016/j.… #CathLab #JACC #Cardiology #AnatomyNerds Kalyanam Shivkumar MD PhD

Visualize the beauty of the heart 🫀: This left anterior oblique view shows septal perforators like you’ve never seen them. The art of precision lives here 🎨 jacc.org/doi/10.1016/j.…

#CathLab #JACC #Cardiology #AnatomyNerds <a href="/shivkumarmd/">Kalyanam Shivkumar MD PhD</a>
JACC Journals (@jaccjournals) 's Twitter Profile Photo

In PROSPECT II, elevated TC, LDL-C, and non-HDL-C were strongly associated with pancoronary #atherosclerosis & lipid deposition, whereas elevated Lp(a) was strongly associated with the presence of focal vulnerable plaques jacc.org/doi/10.1016/j.… #JACC #ASCVD #cvAMI Gregg W. Stone MD

In PROSPECT II, elevated TC, LDL-C, and non-HDL-C were strongly associated with pancoronary #atherosclerosis &amp; lipid deposition, whereas elevated Lp(a) was strongly associated with the presence of focal vulnerable plaques jacc.org/doi/10.1016/j.…

#JACC #ASCVD #cvAMI <a href="/GreggWStone/">Gregg W. Stone MD</a>
JACC Journals (@jaccjournals) 's Twitter Profile Photo

Plaque progression by #YesCCT & #cvPET w/ #PCSK9i? In this prospective study of stable pts w/ extensive quantified non-calcified plaque, 18 months of Tx w/ evolocumab was assoc w/ lower risk plaque & reduced microcalcification. jacc.org/doi/10.1016/j.… #JACCIMG #cvCAD tamarappoo

Plaque progression by #YesCCT &amp; #cvPET w/ #PCSK9i? In this prospective study of stable pts w/ extensive quantified non-calcified plaque, 18 months of Tx w/ evolocumab was assoc w/ lower risk plaque &amp; reduced microcalcification. jacc.org/doi/10.1016/j.…

#JACCIMG #cvCAD <a href="/tamarappoo/">tamarappoo</a>
Amelia Carro — Instituto Corvilud (@icorvilud) 's Twitter Profile Photo

OBESITY-INDUCED CARDIOMYOPATHY ⚖️Epicardial adipose tissue (EAT): a modifiable risk factor ⚖️EAT changes with age and in pathological conditions: early detection is mandatory ⚖️Mechanical, chemical & electric effects➡️CVD ⚖️GLP1ar & SGLT2 inhibitors impact EAT pathologic effects

OBESITY-INDUCED CARDIOMYOPATHY
⚖️Epicardial adipose tissue (EAT): a modifiable risk factor 
⚖️EAT changes with age and in pathological conditions: early detection is mandatory
⚖️Mechanical, chemical &amp; electric effects➡️CVD
⚖️GLP1ar &amp; SGLT2 inhibitors impact EAT pathologic effects
Muthu Vaduganathan (@mvaduganathan) 's Twitter Profile Photo

#CONFIDENCE 1⃣ + 1⃣ = 2⃣ Remarkably, kidney protection with combination therapy mathematically identical to what would be expected based on each monotherapy Finerenone (0.68) * Empagliflozin (0.71) Combination (Expected if Fully Additive): 0.48 Combination (Observed): 0.48

#CONFIDENCE  1⃣ + 1⃣ = 2⃣

Remarkably, kidney protection with combination therapy mathematically identical to what would be expected based on each monotherapy

Finerenone (0.68) * Empagliflozin (0.71)

Combination (Expected if Fully Additive): 0.48

Combination (Observed): 0.48