Nick Rohs, MD (@nickrohsmd) 's Twitter Profile
Nick Rohs, MD

@nickrohsmd

Thoracic Medical Oncology @MountSinaiNY - Clinician, researcher, advocate, & lifelong learner. All tweets/RT are my own thoughts & opinions. #LCSM #LungCancer

ID: 989235792110374912

linkhttps://www.mountsinai.org/profiles/nicholas-c-rohs calendar_today25-04-2018 20:12:46

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Stephen V Liu, MD (@stephenvliu) 's Twitter Profile Photo

#ASCO24 Dr. Prof Tom John shows #MRD analysis from ADAURA (adjuvant osimertinib for #EGFR NSCLC). This is a tumor-informed MRD assay (individual for each patient).

#ASCO24 Dr. <a href="/TommyJohn00/">Prof Tom John</a> shows #MRD analysis from ADAURA (adjuvant osimertinib for #EGFR NSCLC). This is a tumor-informed MRD assay (individual for each patient).
Charu Aggarwal, MD, MPH, FASCO (@charuaggarwalmd) 's Twitter Profile Photo

ctDNA can be a powerful tool to detect relapse before radiographic PD. Terrific presentation by Prof Tom John ASCO #ASCO24 MRD+ detected relapse 4.7 month earlier, and further work needs to be done to select the pts for escalation of tx #LCSM OncoAlert

ctDNA can be a powerful tool to detect relapse before radiographic PD. Terrific presentation by <a href="/TommyJohn00/">Prof Tom John</a> <a href="/ASCO/">ASCO</a> #ASCO24
MRD+ detected relapse 4.7 month earlier, and further work needs to be done to select the pts for escalation of tx #LCSM <a href="/OncoAlert/">OncoAlert</a>
Tom Newsom-Davis (@tnewsomdavis) 's Twitter Profile Photo

CheckMate-77T update ❓Is neo-adj chemoIO appropriate with N2 (poorer prog) St3 ✅ EFS maintained HR 0.60 (N2) v 0.60 (non-N2) ✅ 67% w N2 had nodal downstaging ✅ N2 w/o pCR = ⬆️EFS w Niv HR 0.48 🤔 If resectable, N2 not a reason per se to avoid neo-adj chemoIO #ASCO24 #LCSM

CheckMate-77T update

❓Is neo-adj chemoIO appropriate with N2 (poorer prog) St3

✅ EFS maintained HR 0.60 (N2) v 0.60 (non-N2)
✅ 67% w N2 had nodal downstaging
✅ N2 w/o pCR = ⬆️EFS w Niv HR 0.48

🤔 If resectable, N2 not a reason per se to avoid neo-adj chemoIO

#ASCO24 #LCSM
Lecia Sequist, MD, MPH (@leciasequist) 's Twitter Profile Photo

Really important stage shift shown in Taiwan National Lung screen program. Bravo Dr PC Yang! Family hx is a key risk factor. Excited to collaborate with Allison Chang and Jill Feldman to open a clinical trial soon focused on screening in those w/ a positive family hx #ASCO24

Really important stage shift shown in Taiwan National Lung screen program. Bravo Dr PC Yang! Family hx is a key risk factor. Excited to collaborate with <a href="/aebchang/">Allison Chang</a> and <a href="/jillfeldman4/">Jill Feldman</a>  to open a clinical trial soon focused on screening in those w/ a positive family hx #ASCO24
Benjamin Besse (@benjaminbessemd) 's Twitter Profile Photo

Stop pembro after 2 years? In 43,359 pts that received up-front pembrolizumab for an advanced NSCLC, continuation beyond 2 years was not associated with better OS than a fixed 2-year treatment, HR = 0.97 [0.75–1.26] p = 0.95. Adrien Rousseau sciencedirect.com/science/articl…

Stephen V Liu, MD (@stephenvliu) 's Twitter Profile Photo

What is the role for SRS to brain metastases up front for #EGFR or #ALK NSCLC? Retrospective TURBO-NSCLC study Journal of Clinical Oncology shows early radiation improves CNS control but not survival when CNS-penetrant TKIs are used. Greater benefit with larger tumors. ascopubs.org/doi/10.1200/JC…

Sanjay Popat (@drsanjaypopat) 's Twitter Profile Photo

Excellent paper! Includes England lung cancer never smoking freq by ethnicity. 6.7% of lung cancer are never smokers in White, 38.3% in Indian, 31.6% in Pakistani, 11.3% in Bangladeshi, 14.9% in Caribbean, 39.2% in Black African, & 44.5% in Chinese ethnicities Ruth Strauss Foundation

Ana I. Velázquez Mañana, MD, MSc, FASCO (@anavmanana) 's Twitter Profile Photo

🔑 #LungCancer #ClinicalTrials at #AACR25 ! Zongertinib in pretreated HER2 mut. NSCLC: Beamion LUNG-1 🔹ORR 71% (7% CR) with mDOR 14.1 mo 🔹mPFS 12.4 mo (95% CI, 8.2 to NR) 🔹Intracranial ORR 41% 🔹Pretx with HER2 ADC (cohort 5; n=31) ORR 48% 🔹Improved AE profile compared to

🔑 #LungCancer #ClinicalTrials at #AACR25 !
Zongertinib in pretreated HER2 mut. NSCLC: Beamion LUNG-1
🔹ORR 71% (7% CR) with mDOR 14.1 mo
🔹mPFS 12.4 mo (95% CI, 8.2 to NR)
🔹Intracranial ORR 41%
🔹Pretx with HER2 ADC (cohort 5; n=31) ORR 48% 
🔹Improved AE profile compared to
OncoAlert (@oncoalert) 's Twitter Profile Photo

Surveillance with [18F]FDG PET/CT of stage I-III lung cancer patients after completion of curative treatment (SUPE_R) buff.ly/Pj4cQv4 In the SUPE_R multicenter randomized trial, researchers compared [18F]FDG PET/CT with contrast-enhanced CT (ceCT) for post-treatment

Surveillance with [18F]FDG PET/CT of stage I-III lung cancer patients after completion of curative treatment (SUPE_R) 

buff.ly/Pj4cQv4 

In the SUPE_R multicenter randomized trial, researchers compared [18F]FDG PET/CT with contrast-enhanced CT (ceCT) for post-treatment