Nature Medicine
@NatureMedicine
Nature Medicine is a research journal devoted to publishing the latest advances in translational and clinical research for scientists and physicians.
ID:26832834
http://www.nature.com/nm 26-03-2009 19:53:14
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The hype and hope of new #foodallergy treatments
A paradigm shift is underway with new therapies emerging, including the recent FDA approval of #omalizumab - but it may not be a panacea for all.
News & Views from Prof Kirsten Perrett Murdoch Children's Research Institute (MCRI) University of Melbourne
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Nicotine e-cigarettes: considerations for healthcare providers.
Comment from Benjamin Toll, Tracy T. Smith MUSC Hollings Cancer Center and Brian A. King FDA Tobacco
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A framework for implementing patient-reported outcomes in clinical care: the PROTEUS-practice guide.
Correspondence from Norah Crossnohere The Ohio State University College of Medicine and colleagues.
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The search for authentic microbiome–disease relationships.
A new study challenges the validity of previously reported microbial markers and serves as a wake-up call for the #microbiome research field. News and Views from Ruixin Zhu & colleagues
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An antibody screen of two distinct Multiple Sclerosis cohorts reveals an autoantibody signature that is detectable years before symptom onset and linked to a common microbial motif Gavin Sowa, Colin Zamecnik, PhD, and Ahmed Abdelhak nature.com/articles/s4159…
In a series of clinically relevant tasks in #ComputationalPathology , AI-driven models display performance #disparities across ethnic groups, which self-supervision on large training datasets and existing debiasing techniques can only partially mitigate. nature.com/articles/s4159…
⭐Research highlight: A randomized controlled trial involving a telemedicine-based approach for the management of patients with acute coronary syndrome had several clinical benefits relative to standard of care. JACC Journals
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Controlling for confounders calls into question the robustness of some associations of microbiota with colorectal cancer stages. RaesLab @VIB Sam Van Campenhout #QMP #CRC #MicrobiomeCRCConfounders #QMP MicrobiomeColorectalCancer #GutColorectalcancerQMP nature.com/articles/s4159…
#AI enabled ‘wellness’ apps exist in a regulatory grey area and may pose risks if used to manage #mentalhealth issues. Julian De Freitas & I. Glenn Cohen discuss the potential risks and the implications for app developers and regulators.
Petrie-Flom Center
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Advances in bioengineering and organic chemistry have enabled targeting of the previously ‘undruggable’ #KRAS ; our latest review from Eileen M O’Reilly & colleagues discusses the successes, challenges & future of KRAS therapeutics in #cancer
Memorial Sloan Kettering Cancer Center
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In a randomized clinical trial, alerts based on detection of abnormalities in #Electrocardiograms using a #DeepLearning algorithm reduced all-cause mortality at 90 days in patients admitted to hospital emergency or internal medicine departments. nature.com/articles/s4159…
Climate change and health: understanding mechanisms will inform mitigation and prevention strategies.
Comment from Robbie M. Parks and colleagues Columbia University
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A self-amplifying #mRNAvaccine shows promise in this new modality by eliciting neutralizing antibodies against the SARS-CoV-2 Omicron (BA.1) variant in a phase 2/3 trial.
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Exploratory analysis of the 1-year clinical trial PASADENA in individuals with early-stage #ParkinsonsDisease suggests that prasinezumab might reduce motor signs progression to a greater extent in those with more rapidly progressing disease. #PD Azad Bonni
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In 6 patients with multi-drug resistant #RheumatoidArthritis , the CD19-CD3-targeting bispecific T cell engager #BiTE blinatumomab reduced disease activity and led to reductions in autoantibodies #autoimmunity Ricardo Grieshaber-Bouyer FAU Erlangen-Nbg nature.com/articles/s4159…
Reproductive rights in the United States: acquiescence is not a strategy.
Comment from Dr. Laura Esserman & Douglas Yee MD, as part of our ongoing series on Women's Health
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The QR4 #Algorithm for prediction of 10-year #CardiovascularDisease risk, tested and externally validated in large datasets, improves upon the #QRISK3 algorithm that is in current use by incorporating new risk factors. nature.com/articles/s4159…