NanoFCM (@nano_fcm) 's Twitter Profile
NanoFCM

@nano_fcm

Comprehensive Nanoparticle Analysis

ID: 1252175017036652544

linkhttps://www.nanofcm.com/ calendar_today20-04-2020 10:07:16

17 Tweet

158 Followers

49 Following

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Nano-flow cytometry detects fluorescent particles, identifying phenotypes via labeling. NanoAnalyzer measured GFP-CD63 EVs, calculating concentration & size. GFP+ EVs gated, showing distribution. Antibody staining >95%. NanoFCM's NanoAnalyzer accelerates nanoparticle research!

Nano-flow cytometry detects fluorescent particles, identifying phenotypes via labeling. NanoAnalyzer measured GFP-CD63 EVs, calculating concentration & size. GFP+ EVs gated, showing distribution. Antibody staining >95%. NanoFCM's NanoAnalyzer accelerates nanoparticle research!
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LNP formulation impacts mRNA loading. Conventional methods miss key nanoparticle details. We used NanoAnalyzer to quickly measure mRNA copy number per LNP & distribution for different N/P ratios. #mRNA #LNPs #LipidNanoparticles #RNAEncapsulation #NanoAnalyzer #NanoFCM

LNP formulation impacts mRNA loading. Conventional methods miss key nanoparticle details. We used NanoAnalyzer to quickly measure mRNA copy number per LNP & distribution for different N/P ratios. 
#mRNA #LNPs #LipidNanoparticles #RNAEncapsulation #NanoAnalyzer #NanoFCM
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Analyzing viral vectors made easy with NanoAnalyzer! Correlate surface protein expression & nucleic acid loading for optimized formulations. #CellTherapy #GeneTherapy #NanoFCM #ViralVectors #Adenovirus #Lentivirus #NanoFlowCytometry #NanoparticleAnalysis #NanoAnalyzer

Analyzing viral vectors made easy with NanoAnalyzer! Correlate surface protein expression & nucleic acid loading for optimized formulations. #CellTherapy #GeneTherapy #NanoFCM #ViralVectors #Adenovirus #Lentivirus #NanoFlowCytometry #NanoparticleAnalysis #NanoAnalyzer
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Congrats to Junior Researcher Joseph Brealey on publishing in Journal of Extracellular Biology! The paper explores membrane dyes for labeling extracellular vesicles, identifying options for quick purity assessment.#ExtracellularVesicles #NanoFCM isevjournals.onlinelibrary.wiley.com/.../jex2.70006

Congrats to Junior Researcher Joseph Brealey on publishing in Journal of Extracellular Biology! The paper explores membrane dyes for labeling extracellular vesicles, identifying options for quick purity assessment.#ExtracellularVesicles #NanoFCM

isevjournals.onlinelibrary.wiley.com/.../jex2.70006
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Are you attending #CRSingapore2025, organized by Controlled Release Society ? Join our short seminar and discover workflow solutions for your nanoparticle QC needs!

Are you attending #CRSingapore2025, organized by <a href="/CRSScience/">Controlled Release Society</a> ? Join our short seminar and discover workflow solutions for your nanoparticle QC needs!
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Thrilled to support #ISEV2025 in Vienna (Apr 24-27) again! 🚀 NanoFCM Booth P4: See how our Flow NanoAnalyzer delivers complete EV profiling (size, conc., multi-biomarkers), purity checks & therapeutic insights. Join us! #EVResearch #NanoFCM #EVCharacterization

Thrilled to support #ISEV2025 in Vienna (Apr 24-27) again! 🚀 NanoFCM Booth P4: See how our Flow NanoAnalyzer delivers complete EV profiling (size, conc., multi-biomarkers), purity checks &amp; therapeutic insights. Join us! #EVResearch #NanoFCM #EVCharacterization
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Join Dr. Clayton Deighan at #ISEV2025 lunch session! Learn multicolor EV characterization with Flow NanoAnalyzer. Apr 24, 12:30-1:30 CET, Schubert 1-3. All welcome! #ExtracellularVesicles #MulticolorAnalysis #NanoTechnology

Join Dr. Clayton Deighan at #ISEV2025 lunch session! Learn multicolor EV characterization with Flow NanoAnalyzer. Apr 24, 12:30-1:30 CET, Schubert 1-3. All welcome! #ExtracellularVesicles #MulticolorAnalysis #NanoTechnology
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Save the date! #CYTO2025 by ISAC convenes global cytometry leaders in Denver. Visit NanoFCM at Booth #915 to explore revolutionary single-molecule nanoscale flow cytometry – redefining precision in biomolecular analysis! 📍 Colorado Convention Center 📅 May 31–June 4, 2025

Save the date! #CYTO2025 by ISAC convenes global cytometry leaders in Denver. 

Visit NanoFCM  at Booth #915 to explore revolutionary single-molecule nanoscale flow cytometry – redefining precision in biomolecular analysis! 

📍 Colorado Convention Center
📅 May 31–June 4, 2025
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Off-the-shelf CAR-T skips leukapheresis & custom manufacturing, delivering QC-approved batches in days vs weeks. Game-changing speed for life-saving treatments! How are you optimizing nanoparticle delivery for CAR reprogramming? #CART #CellTherapy #Biotech

Off-the-shelf CAR-T skips leukapheresis &amp; custom manufacturing, delivering QC-approved batches in days vs weeks. Game-changing speed for life-saving treatments!

How are you optimizing nanoparticle delivery for CAR reprogramming? #CART #CellTherapy #Biotech
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In vivo CAR-T uses LNPs to reprogram T cells inside the body (vs. traditional 3-4 week ex vivo process). Key challenge: Targeting LNPs to immune cells via antibodies, ligands, or peptides. #CARTcell #Immunotherapy

In vivo CAR-T uses LNPs to reprogram T cells inside the body (vs. traditional 3-4 week ex vivo process). Key challenge: Targeting LNPs to immune cells via antibodies, ligands, or peptides. #CARTcell #Immunotherapy
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Capstan's LNP tech delivers CAR mRNA to blood T cells in vivo, skipping ex vivo steps. Challenges: protein corona & T cell uptake barriers. Benefits: faster/cheaper, wider cancer applicability, transient CAR expression. #CARTcell #LNPs #mRNAtherapy

Capstan's LNP tech delivers CAR mRNA to blood T cells in vivo, skipping ex vivo steps. Challenges: protein corona &amp; T cell uptake barriers. Benefits: faster/cheaper, wider cancer applicability, transient CAR expression. #CARTcell #LNPs #mRNAtherapy
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Exciting advance in CAR therapy! Myeloid Therapeutics pioneers in vivo mRNA-LNP CARs targeting solid tumors. NanoFCM 's single-molecule analyzer enables precise mRNA/surface ligand quantification, streamlining workflows. DM to explore! #CARTcelltherapy #mRNALNP #Immunotherapy

Exciting advance in CAR therapy! Myeloid Therapeutics pioneers in vivo mRNA-LNP CARs targeting solid tumors. NanoFCM 's single-molecule analyzer enables precise mRNA/surface ligand quantification, streamlining workflows. DM to explore! #CARTcelltherapy #mRNALNP #Immunotherapy
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Thrilled for #APSEV2025 by #SOCRATES! Collab w/ EV societies across APAC. Join our session to decode EV analytics & master precision measurement strategies. #ExtracellularVesicles #EVs #EVAnalytics #FlowCytometry #NanoFCM

Thrilled for #APSEV2025 by #SOCRATES! Collab w/ EV societies across APAC. Join our session to decode EV analytics &amp; master precision measurement strategies. #ExtracellularVesicles #EVs #EVAnalytics #FlowCytometry #NanoFCM
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No #EV gold standard? Optical methods (NTA/DLS/SSC) need assumptions → fail with: • Low-RI EVs • Polydisperse samples • RI heterogeneity Solution: RI-matched beads + Mie theory + SSC calibration ≈ TEM accuracy + speed! #ExtracellularVesicles #NanoFCM

No #EV gold standard?
Optical methods (NTA/DLS/SSC) need assumptions → fail with:
• Low-RI EVs
• Polydisperse samples
• RI heterogeneity
Solution: RI-matched beads + Mie theory + SSC calibration ≈ TEM accuracy + speed!
#ExtracellularVesicles #NanoFCM
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Optimizing nanoscale drug delivery? NanoFCM's analytical workflows help characterize LNPs: ✅ Size/concentration ✅ Empty/full ratio ✅ mRNA copy number ✅ Encapsulation efficiency ✅ Ligand incorporation Hit roadblocks? Let's solve your #LNP challenges together! #DrugDelivery

Optimizing nanoscale drug delivery? NanoFCM's analytical workflows help characterize LNPs:

✅ Size/concentration
✅ Empty/full ratio
✅ mRNA copy number
✅ Encapsulation efficiency
✅ Ligand incorporation

Hit roadblocks? Let's solve your #LNP challenges together! #DrugDelivery
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EMA tightens mRNA-LNP vaccine QC rules: • Particle size • Encapsulation rate • mRNA integrity • Empty LNPs Our integrated CQA testing streamlines compliance - faster, cheaper QC for scalable production. Need analytical solutions? Let's talk. #mRNA #VaccineQC #LNPs

EMA tightens mRNA-LNP vaccine QC rules:
• Particle size
• Encapsulation rate
• mRNA integrity
• Empty LNPs
Our integrated CQA testing streamlines compliance - faster, cheaper QC for scalable production. Need analytical solutions? Let's talk. #mRNA #VaccineQC #LNPs
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🚀 CAR-T Therapy New Era In vivo engineering: faster, safer cancer treatment. 🔬 Join NanoFCM's expert Joseph Brealey's webinar on nanoparticle analysis for CAR therapy QC & development. 👉 Register: nanofcm.com/category/webin… #CART #immunotherapy #genetherapy #LNP

🚀 CAR-T Therapy New Era
In vivo engineering: faster, safer cancer treatment.

🔬 Join NanoFCM's expert Joseph Brealey's webinar on nanoparticle analysis for CAR therapy QC &amp; development. 

👉 Register: nanofcm.com/category/webin…

#CART #immunotherapy #genetherapy #LNP
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🔬 Yes! 10nm LNP size shifts (e.g., 40-80nm vs larger) impact ‌drug delivery potency‌, biodistribution & cellular uptake. Precision sizing now possible via microfluidics. #Nanomedicine #LNP #WhitePaper 👉 Details: nanofcm.com/white-paper/

🔬 Yes! 10nm LNP size shifts (e.g., 40-80nm vs larger) impact ‌drug delivery potency‌, biodistribution &amp; cellular uptake. Precision sizing now possible via microfluidics. #Nanomedicine #LNP #WhitePaper  

👉 Details: nanofcm.com/white-paper/
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🚀 CAR-T Therapy evolves fast! Join Joseph Brealey of NanoFCM to discover game-changing in vivo CAR reprogramming & consolidated analytics for efficient R&D. 🗓️ LIVE: July 24 - 8:00 PT/11:00 ET/17:00 CEST 🔗 Register: nanofcm.com/category/webin…

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‌Flow virometry detects & analyzes viruses (27–100 nm) via light scatter & fluorescence. Calibrated with beads (e.g., QuantiBRITE, Rosetta), it quantifies particle size, concentration, & antigen density (PE MESF/nm²). Proven for HIV-1 & MLV studies. #FlowCytometry #ViralDetection

‌Flow virometry detects &amp; analyzes viruses (27–100 nm) via light scatter &amp; fluorescence. Calibrated with beads (e.g., QuantiBRITE, Rosetta), it quantifies particle size, concentration, &amp; antigen density (PE MESF/nm²). Proven for HIV-1 &amp; MLV studies. #FlowCytometry #ViralDetection