Big day today for the lab, with oral presentation and poster at #ASEICAcongress and flash talk and poster at #EMBLCanGen Cancer Hallmarks and spatial transcriptomics all across Europe!!!

Last year we used spatial transcriptomics from 15 samples to explore how Cancer Hallmarks are distributed in space We have just finished a new version where we analyze 63 tumor samples from 10 cancer types to extend the original findings Here's what we learned 👇

OBS #Cancer #Immunology Seminar 📆 Thu, February 8, 11 am ET/17h CET 🎙️ Mustafa Sibai Josep Carreras Leukaemia Research Institute (IJC) 🎙️ Arja Ray UC San Francisco Moderator Anna Salamero Boix Frankfurt Cancer Institute ✍️ us02web.zoom.us/meeting/regist… #openscience

Congrats Aymara and Paula! Beautiful paper integrating single-cell and spatial transcriptomics to understand the effects of aging in the human myometrium From our end, DanielaGrases did all the spatial data and @mustaphasibai helped with the analyses nature.com/articles/s4146…

So proud of the #SingleCell Spatial Transcriptomics specialists at Josep Carreras Leukaemia Research Institute (IJC)! DanielaGrases, Mustafa Sibai and Eduard Porta collaborate in a cellular atlas to understand myometrium ageing at Nature Communications Read it here 👇👇 nature.com/articles/s4146…

OBS #Cancer #Immunology Seminar TODAY! 📆 Thu, February 8, 11 am ET/17h CET 🎙️ Mustafa Sibai Josep Carreras Leukaemia Research Institute (IJC) 🎙️ Arja Ray UC San Francisco Moderator Anna Salamero Boix Lisa Sevenich Lab Frankfurt Cancer Institute ✍️ us02web.zoom.us/meeting/regist…

First set of Bladder Cancer samples from a Spanish clinical trial, processed with Xenium technology. Looking for spatial predictors of therapy response! Eduard Porta 10x Genomics Mustafa Sibai Josep Carreras Leukaemia Research Institute (IJC)

And it's posted! Comparison of spatial transcriptomics technologies across six cancer types VISIUM + CytAssist + CosMx + Xenium + CytAssist protein On serial sections from 6 human tumors Tweetorial coming tomorrow biorxiv.org/content/10.110…

Last week I had a wonderful time at the #SpatialOmics24 conferences in Ghent, with 2 days full of inspiring talks and mind-blowing advancements in the field of spatial biology and technologies. Also very thankful to the organizers for the oppurtunity to present our latest work.

Thrilled to introduce our Cell Reports @cellreports article, showing how the iconic '#Hallmarks of #Cancer' are located in the space of real human primary tumors. A team effort co-led by Eduard Porta Eduard Porta , Matthew H. Bailey, and yours truly. #SpatialBiology #Visium

The spatial landscape of cancer hallmarks reveals patterns of tumor ecological dynamics and drug sensitivity: Cell Reports cell.com/cell-reports/f… The BATLLE Lab CNIO Stop Cancer OncoAlert Cell Reports

Congratulations 👏🏼👏🏼👏🏼! It's not everyday you get to see one of your favourite preprints published. I was still sharing the preprint results in my teaching on Friday. Can't wait to dive into the final version of this amazing work 🙏🏾.

Raffaele Di Giacomo, PhD The BATLLE Lab CNIO Stop Cancer OncoAlert Cell Reports Thank you for your kind words and thoughtful insights! The integration of spatial biology and tumor ecology indeed has the potential to reshape therapeutic strategies. By understanding the microenvironment and its interaction with tumors, we aim to refine drug selection and

❗️🔬 Researchers led by Eduard Porta reveal that tumour growth depends on position, not just cell types ➡️ By analyzing 63 tumour samples, they revealed that cancer hallmarks—key traits driving malignancy—are spatially organized in patterns Read more👉 carrerasresearch.org/en/news/resear…

Edu is a great postdoc supervisor, and the group he leads consists of exceptionally smart and kind humans. Don't take my word for it, just come join us!

The preprint with DUTRENEO results is out! Beautiful trial design (thx Enrique Grande and Paco Real!) testing TIS in the neoadjuvant setting for bladder cancer + A LOT of spatial data and analyses from Mustafa Sibai DanielaGrases and yours truly medrxiv.org/content/10.110…

Want to take your mind off the whole NIH-indirect costs drama? Interested in spatial transcriptomics, cancer, clinical research, or immunotherapy biomarkers? Then this preprint and tweetorial are for you! 👇👇👇👇👇👇 medrxiv.org/content/10.110…

The scope and scale of this work is nothing short of breathtaking. All we can say is congratulations Eduard Porta, and that your work and approach is demonstrating just how spatial bio is making a brighter future for clinical and drug discovery work. Well done!

#Cancer biomarkers are more than a “what”—they can be a “where,” too. Read our new blog showcasing the DUTRENEO trial preprint, where researchers ID’d spatial biomarkers associated with #bladdercancer treatment response using the Visium platform. Read now! 10xgenomics.com/blog/harnessin…