Excellent opportunity for exceptional postdocs planning to pursue an academic career! I participated in similar programs before going on the job market, and it was incredibly helpful for me. The deadline has been extended to March 25th. Please apply!

Headed to Discover BMB in San Antonio? Come check out our RNA & Gene Regulation Research at Primarily Undergraduate Institutions Interest Group in Saturday morning!
ASBMB, RNA PUI, Nikos Tsotakos, Katie Mouzakis, Dr. Angie Hilliker, Corina Maeder

discoverbmb.asbmb.org/program/intere…

Don't miss out! On March 14th at 12PM EST EpiCypher CSO Michael Keogh will present, 'Next generation epigenetic insight with fully-defined nucleosomes.' Register today: hubs.la/Q02lXzHb0

Product of a collaborative project with the newly minted Dr. Chad Hicks PhD (huge congratulations to same !) : H2BK120 controls access to a hub of nucleosome engagement : the acidic patch. Cynthia Wolberger Chad Hicks EpiCypher, Inc. #nucleosome biorxiv.org/content/10.110…

Full text now out! Fantastic collaboration with EpiCypher, Inc. showing that nucleosome context matters for histone PTM readout, and that patterns of PTMs function both through direct readout and through conformational regulation eLife - the journal Department of Biochemistry and Molecular Genetics Department of Biochemistry and Molecular Biology
doi.org/10.7554/eLife.…

Closing is Remo Rohs presenting powerful AI methods, including Deep DNAshape to predict DNA structure from sequence using deep learning...and much more

#BPS2024 Biophysical Society Meeting

Published just yesterday: nature.com/articles/s4146…

A Zidovska NYU Physics shows exciting work proposing that chromatin behaves as a Maxwell fluid (MF) before differentiation but as a MF + Kelvin solid after. Euchrom activity is critical for organisation

#BPS2024 Biophysical Society

doi.org/10.1103/PhysRe…
journals.aps.org/prx/abstract/1…

Sofia Quinodoz Sofi Quinodoz describing her impressive work with brangwynnelab and Mitch Guttman developing powerful new tools to map nuclear condensates and studying condensate function

#BPS2024 Biophysical Society

More here: doi.org/10.1016/j.cell…
doi.org/10.1016/j.molc…

Next is Maria Mills from Mizzou using single-molecule magnetic tweezers to understand how Msm Topoisomerase I deforms the structure of DNA

#BPS2024 Biophysical Society Meeting

More here: cell.com/biophysj/fullt…

We now have Anupam Mondal from Anatoly B. Kolomeisky group at Rice University presenting theoretical predictions of an important role for nucleosome breathing: facilitating targetting by pioneer transcription factors

More here: pubs.acs.org/doi/abs/10.102…

Meet us at the coffee break now, and after that, we have talks by: Maria Mills, Sofi Quinodoz, @remohs and Alexandra Zidovska

Ritika Gupta Ritika Gupta from Priya Banerjee presents super cool work in collaboration with Emma Morrison and The PotoyanGroup on the thermoresponsive behaviour of mononucleosome condensates and the viscoelasticity of tail/DNA condensates

Come join us in room 107! #bps24

Second is Emma Morrison Emma Morrison discussing their work on phase separation of nucleosomes and how charge-modulating H3 modifications regulate it

More here: doi.org/10.1016/j.bpc.…
and stay tuned for exciting new work systematically probing H3 coming up soon 🔥🔥🔥

First is Mario Halic HalicLab, discussing their cryo-EM work on how Oct4 binds nucleosomes forming dynamic complexes. Histones and their modifications emerged as crucial regulators

Multiscale Genome Organisation Biophysical Society meeting

More here:
nature.com/articles/s4158…

Fantastic collaboration with the Musselman lab that shows why those pesky histone PTMs don't always appear to play together : been looking in the wrong place / way : Nucleosomes don't just CARRY the tails - they regulate their use ...

Happy to share this just out in eLife (full text to follow soon) 👇This was a really great collaboration with EpiCypher, Inc. and very excited about the results! CU Anschutz Medical Campus Department of Biochemistry and Molecular Biology

Excited to be co-organizing the 2024 Van Andel Institute (VAI) Epigenetics Symposium July 8-10. This year's theme will be 'Cancer Epigenetics' with keynote lectures from Drs. Kristian Helin and Steve Baylin. vai.org/event/vai-epig…