Beautiful structure of an #effector from the late blight pathogen bound to a host target by Adam Bentham Mark Banfield. Check the paper out!

I am glad to share the final version of the S. americanum and effectoromics paper. It was posted in BioRxiv and finally published in Nature Genetics, nature.com/articles/s4158…

Join our interdisciplinary MPIPZ Cologne community in Germany and submit your application for a fully financed #PhD program at the #IMPRS! 🗓️deadline for applications for doctoral projects commencing in 2024 is January 6, 2024. 📢spread the word, 👉mpipz.mpg.de/imprs-2021

Come and help lead our efforts in Structural Biology across diverse, exciting and impactful research programs at John Innes Centre and with our partners.

Our new manuscript is out Nature Communications 🎉. Genome-resolved metatranscriptomics reveals conserved root colonization determinants in a synthetic microbiota. nature.com/articles/s4146…. Big Congrats N. Vannier, Fantin Mesny, Felix Getzke, Chesneau Guillaume, Jana Ordon and others MPIPZ Cologne!

New manuscript from our lab in close collaboration with the group of Shaobin Zhong 👇 Our work shows that CNL immune receptors against biotrophic pathogens can be exploited by necrotrophs to induce disease susceptibility! biorxiv.org/cgi/content/sh…

A really exciting opportunity to be part of something special at John Innes Centre and with Norwich Research Park partners. Come and lead our Structural Biology Facility and contribute to a wide variety of projects across discovery science and applied research. Check it out here 👇

Looking for an exciting #PhD or #postdoc opportunity? Come join our lab to study #NLRP1 #inflammasomes or #gasdermin pore formation using #nanobodies and other molecular tools at Institute of Innate Immunity Rheinische Friedrich-Wilhelms-Universität Bonn ImmunoSensation. Please RT.

3D nuclei segmentation using GoNuclear. Kay Schneitz Tejasvinee Mody Qin Yu Soeren Strauss Adrian Wolny Lorenzo Cerrone Fred Hamprecht Richard Smith Lab 🇺🇦 #Anna_Kreshuk github.com/kreshuklab/go-… biorxiv.org/content/10.110…

I am looking for a postdoc to work on understanding mechanisms of gene expression in the chloroplast 🧬🌿. An opportunity for someone interested in doing cryo-EM ❄️🔬and biochemistry 👇

Over 4 years in the making, I am excited to share our pre-print on the “In-cell structure and snapshots of copia retrotransposons in intact tissue by cryo-electron tomography”. We used cryo-ET to resolve the copia capsid structure to subnanometer resolution inside cells. A 🧵

Finally online! First paper from lab! I’m so happy this work found a great home The EMBO Journal read all about how a root barrier does more than just selection! It also signals to the shoot! - a feature thats hidden until you put it plants on a “real” soil doi.org/10.1038/s44318…

@nature, cryo-EM analyses provide insights into how certain NLR proteins are regulated to avoid unintended autoimmunity, while still allowing the host plant to activate effector-triggered immunity when needed. nature.com/articles/s4158…

📢Paper Alert! 🎉🥳New publication out in nature by Paul Schulze-Lefert MPIPZ Cologne and Jijie Chai Westlake University on the packaging of #plant immune molecules to shield them from inappropriate activation.👏👏 Learn more 👉bit.ly/3VtzMb8 nature.com/articles/s4158…

Cytoplasmic calcium influx mediated by plant MLKLs confers TNL-triggered immunity pubmed.ncbi.nlm.nih.gov/38513655/

Our new publication Plant Physiology With a new method we found that a RBA1 variant lacking 2', 3'-CAMP/cGMP synthetase activity but retaining NADase activity does not induce cell death but confers disease resistance. The plasmid is available Addgene

The barley MLA13-AVRA13 heterodimer reveals principles for immunoreceptor recognition of RNase-like powdery mildew effectors

Our lab's review on root rot disease in pea, detailed discussion on current challenges and how new technologies can help tackle them!! Nicolas Trenk and Alba Pacheco Moreno