Systemic inflammation & plaque progression by #YesCCT? Study alterations in atherosclerotic plaque progression were correlated w/ Hs-CRP. Total plaque progression was 1.4-fold higher. bit.ly/3OSgGc8 #JACCIMG #PARADIGM Solomon W. Bienstock, MD Ron Blankstein Leslee Shaw

Brilliant work, congratulations 👍🍀😀

This review from Dr. Kenneth Walsh et al. focused on the association between environmental stressors and inherited genetic risk factors in the context of #CH development. oaepublish.com/articles/jca.2…

Glückwunsch an Thorsten Keßler und Steffen Massberg zum Albert-Fraenkel und Paul- Morawitz-Preis👏🎉

Nice that you were all there. 🙋DZHK meet & greet at the #DGK2024JT Young-DZHK

Excited to share our study on BioRxiv! We developed a spatial proteomics approach combining multiplexed imaging & deep visual proteomics to profile tumor-immune interactions. Discover how our findings can inform new immunotherapy targets and strategies! 🔗 doi.org/10.1101/2024.0…

We are proud to announce that Ruedi Aebersold, founder of our institute and beloved colleague, will be awarded the Dr H.P. Heineken Prize for Biochemistry & Biophysics 2024. He receives it together with Matthias Mann Lab for their groundbreaking contributions to proteomics ETH Zurich

Excited to share our new findings on loss of Y chromosome affecting cardiovascular outcome in patients with chronic kidney disease 😀 special thx to our nephrologist T. Speer 👍🍀 DZHK Germany Stefanie Dimmeler CPI European Research Council (ERC) @FaiezZannad Caitlyn Vlasschaert Lars Forsberg

Our study led by Marian Zuriaga Zhi Yu & with José Javier Fuster uses murine & human genetic studies to infer that individuals with TET2 clonal hematopoiesis may derive potent CV risk-reduction with colchicine academic.oup.com/eurheartj/adva… European Society of Cardiology Journals 🟢Colchicine has been proposed

And another paper online simultaneously with #ESCCongress! With Dr. Valentin Fuster and colleagues CNIC, we clarify the relationship between clonal hematopoiesis and atherosclerosis. Nature Medicine nature.com/articles/s4159… More details ➡️ bit.ly/3Z8hi38

Important insights into longitudinal CHIP dynamics and potential drivers 👍🍀😀

1/ 🧵Introducing UNICORN,🦄 the first #AI model for integrating multi-stain #histopathology images for classification, designed to tackle missing data during both training and inference. Great colab between Helmholtz Munich | @HelmholtzMunich & TU München German Heart Centre! the architecture ⬇️

Our latest publication JAMA Cardiology: We identified 17 #AorticStenosis specific genetic loci, including 5 novel loci. Serum #phosphate is a unique AS risk factor. Our findings reveal AS's distinct pathways from #CAD, paving the way for targeted therapies. ➡️bit.ly/4ezb2pq

Prasugrel proves more effective than ticagrelor in clinical practice when emulating the randomized trial ISAR-REACT5 in claims. Hot off the press w/ johannes krefting Hendrik B. Sager Moritz von Scheidt

Mosaic loss of Y chromosome portends a high risk of mortality after coronary angiography. Read more in #EHJ 👉 bit.ly/4aU5upd Rocco Montone EHJ Editor-in-Chief

Plaque erosion is a main mechanism for myocardial infarction: JAK2 V617F linked to erosion risk doi.org/10.1093/eurhea… #MI #CAD #cardiotwitter, European Society of Cardiology Journals, European Society of Cardiology

Our paper on ovarian cancer #LGSC is out in Cancer Cell. Using deep visual proteomics #DVP and spatial transcriptomics, we mapped how non-invasive tumors become deadly ovarian disease, and found a promising new treatment combination. cell.com/cancer-cell/fu…

🚨 Excited to share that our latest study on the role of inflammatory activation in endothelial cells during the infarct response is now published in Circulation Research! Huge thanks to all co-authors especially Lukas, Till, Simone, and Ariane for driving this project forward.

In >8,600 CAD patients, CHIP was linked to higher mortality, visualized in plaque macrophages, and associated with plaque vulnerability. We uncovered a novel mechanism where TET2-CHIP drives lipid uptake & inflammation—making it a targetable source of residual risk. @DZHK_germany

In a study in Science, a team of researchers have mapped how thousands of proteins in human blood shift as a result of aging and diseases. The molecular "fingerprints" from 59 diseases can enable blood tests to discern troubling signs from common. proteinatlas.org/news/2025-10-0…