Structuring Role of Tau-Tubulin Co-Condensates in Early Microtubule Organization doi.org/10.1101/2024.1…

The ability to model both folded domains and disordered regions in condensates means that we can now begin to use CALVADOS simulations to ask how and why the condensate environment changes folding stability

Diamonds are a physical chemist's best friend! Researchers at College of Chemistry SLAC National Accelerator Laboratory Lawrence Livermore National Laboratory Science at Melbourne collaborate to capture the structural response of diamond films excited with intense ultrafast laser pulses in search of liquid carbon. pubs.acs.org/doi/full/10.10…

A blueprint for biomolecular condensation driven by bacterial microcompartment encapsulation peptides doi.org/10.1101/2024.1…

In Cell, I share a major conceptual challenge for biology in the next decade, inspired by Crick’s Central Dogma: understanding information flow in the cell, the smallest indivisible unit of life bit.ly/4hQMmva

Happy to share the final program of the Intrinsically Disordered Proteins Subgroup (IDP Subgroup) symposium at the Annual Meeting of the Biophysical Society that will be held in Los Angeles on February 15, 2025 BPS IDP Subgroup Biophysical Society. biophysics.cld.bz/Biophysical-So…

Birth of protein folds and functions in the virome | Nature nature.com/articles/s4158…

Happy to share the final program of the 2025 Intrinsically Disordered Proteins Subgroup Symposium at the Biophysical Society Meeting to be held in Los Angeles on February 15. Looking forward to seeing you all in less than a week BPS IDP Subgroup Biophysical Society.

Glad to share recent findings from the lab. Khushboo's Khushboo Rani (She/her) efforts & Bharat's Bharat Gurnani contributions paid off!! Probing a salt‐induced conformational switch in β2‐microglobulin under low pH conditions. febs.onlinelibrary.wiley.com/doi/10.1111/fe…

Happy to share our latest paper published in Science Advances Science Advances @AAAS. Congratulations to my incredible students, Sandeep Sandeep Kumar Rai, Roopali Roopali Khanna (joint-first author), Anusha Anusha Sarbahi & Ashish Ashish Joshi @IISERMohali. science.org/doi/10.1126/sc…

Happy to share our recent paper in RSC Advances Royal Society of Chemistry from our collaborative effort with Dr. Maity Banibrata Maity Thapar Institute of Engineering & Technology Congratulations to our PhD student Mandeep Kaur Mandeep Kaur (She/ Her). Read our paper: pubs.rsc.org/en/content/art…

Very excited about the first PhD from my lab Thapar Institute of Engineering & Technology: Many congratulations to Dr. Deepika Singla Deepika for defending her PhD thesis successfully.👏 Thanks to Prof. Swagata Dasgupta (IIT KGP) & doctoral committee! All the best, Deepika, for your continued success!👍

Happy to share our latest review article, highlighting how phase separation—driven by protein–protein and protein–RNA interactions—underpins the organization of ribosome assembly within the nucleolus. sciencedirect.com/science/articl…

It was wonderful to speak with the.scicomm.synapse yesterday. If you want to watch my interview, here's the link (duration: 1h40m; if you want, you can watch it at a 1.25x playback speed). youtube.com/live/6V1OOnctq…

Biomolecular condensates as regulators of enzymatic reactions: nature.com/articles/s4428…

We invite postdocs interested in faculty positions to join us for an interactive Young Researchers Meeting on 2 August 2025. Hear from the Director, Deans & faculty members, and find out what IISc has to offer! Register by 12 noon (IST) on 1 August at: docs.google.com/forms/d/e/1FAI…

Amino acid transfer free energies reveal thermodynamic driving forces in biomolecular condensate formation | PNAS pnas.org/doi/10.1073/pn…

Happy Diwali from the Mukhopadhyay lab! On the occasion of Diwali, the festival of lights, I share a video of the formation-dissolution of multi-component multi-phasic protein-RNA condensates prepared and imaged (using 488 nm & 594 nm lasers) by my students, Sandeep and Roopali.

Happy to share our latest paper published in PCCP (Physical Chemistry Chemical Physics) PCCP Royal Society of Chemistry. Congratulations to my PhD student, @Jaspreet_Tiet Thapar Institute of Engineering & Technology. Thanks to ANRF-POWER and MoE-STARS for supporting our research. Here's the link: pubs.rsc.org/en/content/art…