This is an incredible finding that may go a long way to explain cancer type-specific copy number alteration patterns (in addition to selection which - if I am to guess - will be a smaller part of the story). Really mind-blowing work @KopsLab !!! nature.com/articles/s4158…

Want to learn the clonality and relatedness of your single cell transcriptomes? Are you really into X-inactivation? Want another reason to stop sequencing men? Try our method, github.com/constantAmateu…, read our preprint, biorxiv.org/content/10.110…, and read this thread... 👇🧵