Our multiomic screen of the changes triggered by acute #stress in the hippocampus is now out in NatureCommunity 🥳 Don't miss the wild preprint trailer👇and follow the 🧵 to find out what has changed during the review process. We added (and removed!) a lot! nature.com/articles/s4146…

Wild new research tool alert!🤯If you plug a research question into elicit.org, it uses AI to not only find relevant papers but pulls out ANSWERS from the papers. Adding to my list of things that would've changed the game at the start of my PhD #AcademicTwitter

Very happy to share my lab’s new paper out in @PNAS. doi.org/10.1073/pnas.2…

Locus Coeruleus firing patterns selectively modulate brain activity and dynamics biorxiv.org/cgi/content/sh… #biorxiv_neursci

NEW PREPRINT FROM THE LAB📢📢: Locus Coeruleus firing patterns selectively modulate brain activity and dynamics! 3y in the making and this work is finally seeing light thanks to a fantastic teamwork! C Grimm, S Duss and Johannes Bohacek. Short thread ⬇️ biorxiv.org/content/10.110…

The locus coeruleus mediates behavioral flexibility biorxiv.org/cgi/content/sh… #biorxiv_neursci

The gene expression landscape of the human locus coeruleus revealed by single-nucleus and spatially-resolved transcriptomics biorxiv.org/cgi/content/sh… #biorxiv_neursci

For the first time, farmers in the #Philippines have cultivated #GoldenRice on a larger scale and harvested almost 70 tonnes of grains this October.This nearly never-​ending story began at ETH Zurich. #betacarotene #vitaminA #HiddenHunger ethz.ch/en/news-and-ev…

New Nature paper provides evidence that science has become less innovative since the 1950s. The authors suggest reversing the trend by: 1. reading widely, 2. focusing less on quantity of papers, & more on research quality, 3. taking year-long sabbaticals. nature.com/articles/s4158…

🔵 In 2016 I wrote a grant, in which Mattia Privitera and I asked a simple question: Stress triggers massive transcriptional changes, which of them are dependent on noradrenaline (NA) signaling? Today, we have the answer. But boy was this a journey. 🧵👇 biorxiv.org/content/10.110…

1st preprint of the Gapplab! Check out our PROTAC tool to mingle with stress hormone receptor signalling A fun collaborative effort by @Carreiralab Johannes Bohacek @bel_ethz Meijer Lab Pierre-Luc Germain Lead by stellar students @MGazorpak & Karina Hungentobler biorxiv.org/content/10.110…

🚨In our latest preprint🚨 we propose a radical change to the analysis of rodent #behavior in preclinical research. Featuring DeepLabCut 🦄 ♥️ Check out the manuscript and the 🧵👇 x.com/biorxiv_neursc…

That's all folks! You gave me everything. I gave you everything. We did it together.

A new review paper led by Martin J. Dahl, Agnieszka Kulesza and M. Werkle-Bergner. We review how deficient #dopaminergic and #noradrenergic modulation of hippocampal plasticity may contribute to memory loss in aging and Alzheimer's disease sciencedirect.com/science/articl… #locuscoeruleus

The first cellular map of a mammalian brain is here. 🧠✨ Over 6 years and 32 million cells in the making, the complete adult mouse brain cell-type atlas reveals astonishing diversity and regional specificity. Dive deeper: alleninstitute.org/scientists-unv… @nature #studyBRAIN #BICCN

I am not on instagram but thanks to SRF our PROTAC is Johannes Bohacek @MGazorpak CarreiraGroup @bel_ethz Miriam Kretschmer @SelinaJoyFrei Iryna Ivanova Mattia Privitera instagram.com/reel/C2fnYdBOK… srf.ch/play/tv/srf-ne…

🔵 Noradrenaline directly regulates gene expression in the brain. 8 years in the making, now finally published in eLife - the journal 🥳 During revisions, we added 32 RNAseq samples and a meta-analysis of 71 RNAseqs to rule out major sex differences. #stress Please RT elifesciences.org/articles/88559

Out now in Nature Neuroscience: "Centripetal integration of past events in hippocampal astrocytes regulated by locus coeruleus", nature.com/articles/s4159… With a great team: @FritjofHelmchen Johannes Bohacek Sian Duss chris lewis and (twitterless) Denise Becker. 1/5

And Eli Bueicheku showed that #locuscoeruleus changes may precede cortical tau, predicting future cognitive decline. She also highlighted some of the genetic features associated with this spatial pattern of tau vulnerability! With Jorge Sepulcre Lab Nature Aging 🎉 nature.com/articles/s4358…

During moderate tonic locus coeruleus activation in mice, noradrenaline release engages cortical regions related to associative processing, while burst-like stimulation biases the brain toward sensory processing nature.com/articles/s4159…