Happy to announce my PhD work is published!🎉
PNASNews : Myospreader improves gene editing in skeletal muscle by myonuclear propagation pnas.org/doi/10.1073/pn…

Paper #3 in Nature Communications: nature.com/articles/s4146…

Septin 7 interacts with Numb to preserve sarcomere structural organization and muscle contractile function
elifesciences.org/articles/89424

Paper #4 in Function: academic.oup.com/function/advan…

MoTrPAC Study Group Paper #6 in Cell Metabolism

The mitochondrial multi-omic response to exercise training across rat tissues: Cell Metabolism cell.com/cell-metabolis…

SETDB1 modulates the TGFβ response in Duchenne muscular dystrophy myotubes
science.org/doi/10.1126/sc…

Learn how key 🔑 transcription factors and cofactors such as the Mediator complex cooperate to regulate #myogenesis .

Scientists show that Med23 deficiency in MuSCs decreases proliferation and promotes precocious differentiation.

bit.ly/3WkMwCH

New Developmental Cell paper from Nadia Mercader & colleagues: Cox7a1 controls skeletal muscle physiology and heart regeneration through complex IV dimerization. tinyurl.com/5n87fdx5

New PNASNews paper: Neuronal innervation regulates the secretion of neurotrophic myokines and exosomes from skeletal muscle. tinyurl.com/ya66mjkp

The new Mitchell model of OXPHOS in skeletal muscle. rdcu.be/dwqbw

Nature Metabolism Formentini Lab Centro de Biología Molecular Severo Ochoa UAM Autónoma Madrid FundaciónRamónAreces

Pleased to share follow up study to earlier work on the mdm mouse model (titinopathy) showing mechanosensitivity of ANKRD1.
Many thanks to Drs. Pardo, Mohamed, and Boriek!

link.springer.com/article/10.100…

Check out the most recent preprint from Christopher Perry PhD and the team. Great work showing the potential of adiponectin receptor agonism in muscle wasting !

Temporal dynamics of the multi-omic response to endurance exercise training | Nature nature.com/articles/s4158…

New PNASNews paper: Development of porcine skeletal muscle extracellular matrix–derived hydrogels with improved properties and low immunogenicity. tinyurl.com/2nnj3kd7

So excited to finally see this work published! 🙌

#PLOSONE : An optimized approach to study nanoscale sarcomere structure utilizing super-resolution microscopy ... dx.plos.org/10.1371/journa…

#myotwitter

cell.com/cell-reports/f…

We’re happy to share our most recent paper about LSD1 inhibition circumvents glucocorticoid-induced muscle wasting of male mice published Nature Communications Qingshuang Cai IGBMC nature.com/articles/s4146…

New #SkeletalMuscle paper: Pannexin 1 dysregulation in Duchenne muscular dystrophy and its exacerbation of dystrophic features in mdx mice. tinyurl.com/bh9uytj4

Very excited to share our latest work on DMD skeletal muscle transcriptomics identifying a BMP4 molecular signature in severe DMD muscle. A fantastic collaboration with Matthew S. Alexander, Merry-Lynn McDonald, David Crossman, Peter King and team.
👇🏽
biorxiv.org/content/10.110…

Distinct transcriptomic profile of satellite cells contributes to preservation of neuromuscular junctions in extraocular muscles of ALS mice
elifesciences.org/articles/92644