Looking for a Marie Curie PhD project focused on cross-coupling reactions with base-metal catalysts? Check out the NextBase website for open positions: nextbase.network APPLY NOW!!!

A Tight Contact: The Expanding Application of Salicylaldehydes in Lysine-Targeting Covalent Drugs (A. Dal Corso et al.) Mattia Mason Alberto Dal Corso Luca Pignataro Università degli Studi di Milano #openaccess onlinelibrary.wiley.com/doi/10.1002/cb…

Amine-Carbamate Self-Immolative Spacers Counterintuitively Release 3° Alcohol at Much Faster Rates than 1° Alcohol Payloads (A. Dal Corso et al.) Mattia Mason Luca Pignataro Alberto Dal Corso Università degli Studi di Milano onlinelibrary.wiley.com/doi/10.1002/cb…

Check out our last article on the cyclative release of similar |, || or ||| alcohol payloads from carbamate prodrugs! SPOILER: the primary alcohol takes its time. Congrats to birthday boy Mattia Mason and the whole team!

It seems our 2023 article on self-immolative spacers is one of the most downloaded of the year for ChemMedChem! Great to have this feedback and thanks to Alena Lasater for making this work #OpenAccess!

This is our latest effort towards Lys-binding, reversible-covalent peptides. Congrats to Mattia Mason and stay tuned for more updates!