
Maria A Perry
@mariaaperry
she/her ✨ | MSKCC 💻🧬 | @MIT & @WeillCornellGS alum 🦫👩🏻🔬
ID: 1319471696630452225
23-10-2020 02:52:33
16 Tweet
47 Followers
254 Following






At #AACR23 the coming days with lots of folks from Niki Schultz's lab! Come say hi! Find us at the cBioPortal and OncoKB™ booths most days. Feel free to DM if u want to meet up


Thrilled to share our recent work in Cell ✨ We study the extent to which tumor suppressor genes in cancer adhere to Knudson's ‘two-hit’ hypothesis, and their clinical implications. 🧵👇 Also a detailed 🧵 by Ed Reznik below: MSK Department of Pathology & Laboratory Medicine Memorial Sloan Kettering Cancer Center


🧬KRAS mutations in pancreatic cancer Nature Medicine 🚨95% of pancreatic cancers are KRAS mutant ❗️KRAS mut-allele dosage 🔺,OS🔻 ⁉️Targetting KRAS! 👉doi.org/10.1038/s41591… Eileen M O’Reilly Olca Basturk OncoAlert Dr Joseph McCollom DO Arndt Vogel #cancer #oncology #MedX


Excited to share our latest in Nature Medicine✨ We present a detailed clinico-genomic landscape of pancreatic adenocarcinomas With important implications for RAS 🎯 therapies Expertly co-led by Anna Varghese and Maria A Perry. w/Eileen M O’Reilly & colleagues Memorial Sloan Kettering Cancer Center


Paper: nature.com/articles/s4159… Data for 2,336 patients with PDAC on cBioPortal: cbioportal.org/study/summary?… MSK Department of Pathology & Laboratory Medicine MSKCC Center for Pancreatic Cancer Research MSK Department of Medicine

That KRAS Wild type #PancreaticCancer is a distinct entity from KRAS mutant disease was also recently reported by Eileen M O’Reilly & colleagues in their single institution study from Memorial Sloan Kettering Cancer Center in Nature Medicine nature.com/articles/s4159…

Featured today by MSK Library: Pan-cancer analysis of biallelic inactivation in tumor suppressor genes identifies KEAP1 zygosity as a predictive biomarker in lung cancer #BiallelicInactivation #TumorSuppressorGenes #LungCancer #CancerBiomarkers #KEAP1 #PrecisionOncology
