Study by Prof. Bushra Ateeq & team uncovering the role of KIT signaling in lineage plasticity in SPINK1-elevated prostate cancer -offering new treatment modalities for advanced-stage SPINK1-positive patients pubmed.ncbi.nlm.nih.gov/38384854/ BSBE@IITK Mehta Family Foundation Bushra Ateeq #CancerResearch

An integrative proteomics approach identifies tyrosine kinase KIT as a therapeutic target for SPINK1-positive prost… pubmed.ncbi.nlm.nih.gov/38384854/

Our group has openings for PhD positions in Cancer Biology/Cancer Genomics with a translational focus. We are unraveling the functional and clinical significance of the major gene alterations discovered in cancer patients from India. Deadline for application is 11 April (1/2)

Hot 🔥 off the press from Shivdasani Lab! Transcription factor dynamics, oscillation, and functions in human enteroendocrine cell differentiation. A magnum opus from my dear friend Pratik. Thrilled to be a part of this study 🙂 Cell Stem Cell cell.com/cell-stem-cell…

Our heartfelt congratulations to Prof. Bushra Ateeq on assuming the position of Dean of International Relations. Prof. Ateeq is a Professor & Joy-Gill Chair, and Senior Fellow of the DBT/Wellcome Trust India Alliance. #IITKFaculty #internationalrelations #IITKanpur #iitk

Check out our new review in Nature Reviews Urology on biologic determinants of PSMA expression, regulation, and heterogeneity in prostate cancer led by Martin Bakht Dana-Farber Lank Center for Genitourinary Oncology PCF Science Link to paper: rdcu.be/dM7GF nature.com/articles/s4158…

Proud to share our paper Journal of Clinical Investigation led by ShengYu Ku Dana-Farber with #GoodrichLab Roswell Park: Notch signaling suppresses neuroendocrine differentiation and alters the immune microenvironment in advanced prostate cancer PCF Science jci.org/articles/view/…

Congratulations Balaji! Our new paper Nature Communications highlights the context specific role of EZH2 in prostate cancer. Thank you to many collaborators Myles Brown Rickman Lab and funding support Prostate Cancer Foundation DF/HCC National Cancer Institute #SPORE rdcu.be/dQo0P Dana-Farber #BeltranLab

Check out our paper on lineage-specific activity of EZH2 in advanced #ProstateCancer subtypes published in Nature Communications. Thank you Misha Beltran for strong support! #BeltranLab PCF Science CDMRP National Cancer Center Dana-Farber Lank Center for Genitourinary Oncology nature.com/articles/s4146…

Our study on sex differences in Xp11 translocation renal cell carcinoma is out Cell! We ascribe a genetic basis to the female bias in tRCC, which is driven by a translocation of the TFE3 gene on the X chromosome. w Zhang lab @danafarbernews bit.ly/4dtpNtP 🧵1/

A year after we put it at bioRxiv, I am thrilled to see our work and effort on female sex-bias of translocation renal cell carcinoma (tRCC) to be finally online on Cell! A 🧵 cell.com/cell/fulltext/…

Thanks to TWAS - The World Academy of Sciences for recognizing our research efforts in #combating cancer. #TWAS award in Medical & Health Sciences is a testimony of the hard work and dedication of my past and present group members. TWAS announces 2024 slate of awards twas.org/article/twas-a…

The diagnosis of neuroendocrine prostate cancer is often challenging. Here is our perspective Clinical Cancer Research on the pathologic work-up of NEPC. With #MHaffner Brian Robinson ROHIT MEHRA Tamara Lotan, MD Mark A. Rubin and many other great colleagues PCF Science pubmed.ncbi.nlm.nih.gov/39589343/

Another achievement from ⁦Dana-Farber Lank Center for Genitourinary Oncology⁩ superstars ⁦Dana-Farber⁩ ⁦Misha Beltran⁩ ⁦Heather Jacene⁩ ⁦Praful Ravi⁩ as part of Team Science working on the Nuclear Medicine Theranostics

In memory of Dr. Felix Feng. Thank you European Urology for honoring our beloved colleague and friend, gone too soon. We miss you Felix Mary Feng Nancy Lin, MD PCF Science sciencedirect.com/science/articl…

Sharing biological insights on targeting EZH2 in advanced #ProstateCancer subtypes from our recent paper in Nature Communications. Thank you for hosting me, Andrea Miyahira UroToday.com! #BeltranLab Misha Beltran Dana-Farber Lank Center for Genitourinary Oncology

Excited to share our latest article on exploring the surfaceome and targeting surface antigens in prostate cancer! Huge thanks to Misha Beltran, Johann de Bono, Tarek Taha and Balaji for all the support! 🙌 nature.com/articles/s4158…

I am excited to share my Postdoctoral work Dana-Farber Cell Stem Cell Cell Press (dlvr.it/TK2Fzl). Here, we reveal that goblet and Paneth cells aren’t fixed lineages but represent dynamic states influenced by local cues. Here's a walkthrough of what we found (🧵)....

CircRNA is the most bizarre yet fascinating RNA. Our work of circRMST in prostate and lung cancer is now online at Cancer Cell. Great teamwork with Misha Beltran and Jun Qing and many others. Thanks for the support from Terry Fox Research Institute Prostate Cancer Foundation The Princess Margaret Cancer Foundation CIHR and more

Intraindividual epigenetic heterogeneity underlying phenotypic subtypes of advanced prostate cancer Nature Communications rdcu.be/euijO Team science led by Kei Mizuno #BeltranLab Dana-Farber Lank Center for Genitourinary Oncology PCF Science