Check out AMAP, our fully automated algorithm for segmentation and quantification of foot process morphology. Great collaborative effort with ⁦David Unnersjö-Jess⁩ ⁦Kasia Bozek⁩ ⁦Martin Höhne⁩ ⁦Bernhard Schermer⁩ and more biorxiv.org/content/10.110…

The glomerular filtration barrier: a structural target for novel kidney therapies go.nature.com/36Eh6fH - find out about the potential for a new generation of drugs for kidney diseases in this new review by Ilse Daehn, PhD Barbara T. Murphy Mount Sinai Div. of Nephrology Mount Sinai Department of Medicine and Jeremy Duffield @DuffieldLab

A fantastic start to #podocyte2021 - the pre-meeting organised the amazing early career team ⁦Franziska Lausecker⁩ ⁦Richard W Naylor⁩ ⁦Maryline Fresquet⁩ ⁦Pinyuan Tian⁩ ⁦Kate Sybert⁩ & ⁦Linus Butt⁩ - congrats! You have set the bar high!! ⁦Podocyte2021⁩

New preprint for all you paraffin embedding-lovers out there, with Amer Ramdedovic Linus Butt Martin Höhne Bernhard Schermer and others.

Great to see our recent review on the current knowledge of #RNA-binding proteins in #kidney disease and potential therapeutic implications published online by Nature Reviews Nephrology. Wonderful work, @SisaLeufert and the great team CECAD Cologne Universität zu Köln Uniklinik Köln nature.com/articles/s4158…

Mice carrying a common mutation in the gene encoding podicin show signs of podocyte injury as they age and after injection with a nephrotoxin—suggesting that the mutation confers a genetic predisposition to glomerular disease bit.ly/j202006085 Martin Höhne

📣 🆕 𝗜𝗦𝗡 𝗩𝗜𝗗𝗘𝗢 𝗔𝗕𝗦𝗧𝗥𝗔𝗖𝗧 𝗦𝗘𝗥𝗜𝗘𝗦: A mathematical estimation of the physical forces driving podocyte detachment. 2021 from Kidney International kidney-international.org/article/S0085-… Linus Butt David Unnersjö-Jess Martin Höhne Bernhard Schermer

Which longevity-associated dietary intervention protects best from ischemia-reperfusion injury? Check out Felix Koehler's recent work bit.ly/35l38Sq to find the answer and some insights into a convergent metabolic response. #diet #kidney #longevity

19) Thank you for coming back! You are learning from Hans-Joachim Anders all about #CKD + #T2D while you earn 🆓CE/#CME! Hello to Kenar Jhaveri Christoph Kuppe Tiffany Caza Astrid Weins Susan Allison Linus Butt Renal Pathology Society Jean Hou, MD Christoph Wanner Muthu Vaduganathan Kuang-Yu Jen, MD, PhD

Finally heading for our nephrolab retreat! 🏝🏝🏝

Our meeting report on the 13th International Podocyte Conference 2021 is out. Thanks to the fabulous Rachel Lennon Rachel Lennon and her team and all other authors. Kate Sybert @fab_braun Linus Butt Franziska Lausecker Maryline Fresquet pubmed.ncbi.nlm.nih.gov/35964799/

Caloric restriction protects from #kidney injury in rodents. But translation to humans requires unravelling the molecular mechanisms. A spotlight on NAD de novo biosynthesis and acetylation of metabolic enzymes. Universität zu Köln CECAD Cologne Uniklinik Köln see 🧵below journals.lww.com/jasn/Abstract/…

New preprint out. Using 3D high-resolution imaging, we found that the orientation of podocyte processes is likely governed by the mechanical forces acting on them. Thanks to all co-authors! Amer Ramdedovic Linus Butt Martin Höhne Bernhard Schermer biorxiv.org/content/10.110…

Our study on deep learning-based segmentation and multi-parameter morphology analysis of foot processes is online! Thanks for a great collaboration Linus Butt Kasia Bozek Martin Höhne Bernhard Schermer kidney-international.org/article/S0085-…

Deep learning–based segmentation and quantification of #podocyte foot process morphology suggests differential patterns of foot process effacement across #kidney pathologies doi.org/10.1016/j.kint… #ArtificialIntelligence #pathology KTH Royal Institute of Technology Universität zu Köln

Advanced optical imaging reveals preferred spatial orientation of #podocyte processes along the axis of glomerular capillaries. doi.org/10.1016/j.kint… #glomerulus #ultrafiltration

We have a freshly funded consortium in eye medicine in Cologne with plenty of challenging image analysis tasks ahead. We're looking for a postdoc, please spread/apply! euraxess.ec.europa.eu/jobs/183995

We perform a fully unsupervised analysis of the filtration barrier in kidney and show that it allows to group images in a way that reflects their morphometry: frontiersin.org/articles/10.33… Great collaboration with the NephroLab David Unnersjö-Jess Linus Butt !

One of the most pressing questions in the era of caplacizumab is if iTTP can be managed without plasma exchange! Check out our paper addressing this question: Management of Immune Thrombotic Thrombocytopenic Purpura without Therapeutic Plasma Exchange ashpublications.org/blood/article-…

Projekt-Manager für ein großes klinisches Studienprojekt (im Bereich Nephrologie) gesucht, multizentrische IIT (AMG). Lust in einem engagierten Studienteam mitzuarbeiten? Eine internationale Studie zu koordinieren? Dann sehr gerne direkt bei mir melden.