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Absolutely honored that our project caught the eye of a global biotech leader like CSL expediting innovative biotherapy discovery. Collaborative synergy with academia and private sector accelerated medical research innovation I2MC-Toulouse INSPIRE Platform - IHU HealthAge newsroom.csl.com/index.php?s=20…

Next week we will have again our internal seminar on Tuesday February 6 at 11 a.m. followed by an aperitif🥮 to continue to discuss science. Amandine Wahart from the Archi-Card team and Zichun Cai from the LiMitAging team will present their work.

Congratulations to the new IHU HealthAge team in Toulouse for "Integrative multi-modal metabolomics to early predict cognitive decline among Amyloid positive community-dwelling older adults." pubmed.ncbi.nlm.nih.gov/38452244/ Isabelle ADER Bruno Vellas @RestoreInstitut Infinity Toulouse @i2mc

Happy to share this new study from I2MC-Toulouse & IHU HealthAge Team in Toulouse at INSPIRE Platform - IHU HealthAge Targeting adipose P2Y13-R activity may represent a pharmacological strategy to prevent #age-associated disorders, including #diabetes and #MASLD JCI insight insight.jci.org/articles/view/…

Online now! Trigonelline is an NAD+ precursor that improves muscle function during ageing and is reduced in human sarcopenia dlvr.it/T4J4LW

In this new study conducted with MetaDiab_Lab within the #IHUHealthAge, we reported that ApoM decreased with age and negatively associated with insulin resistance INSPIRE Platform - IHU HealthAge I2MC-Toulouse nature.com/articles/s4136…

What an excellent meeting in Albuquerque covering basic and clinical research in Geroscience Geroscience Pre-Clinical and Clinical Trials

The French Purine Club is happy to introduce you to the speakers for our second Webinar: Pr. Maria Domercq Pr. Kenneth Jacobson Pr Alexander Pfeifer To attend the webinar, save the date and please follow the link: u-bordeaux-fr.zoom.us/j/81139788609

Will the Gates Foundation’s preprint-centric policy help open access? nature.com/articles/d4158…

Mitochondrial respiration atlas reveals differential changes in mitochondrial function across sex and age biorxiv.org/content/10.110…

Thrilled to be associated with this study from Alexander Bartelt, Vivian R. M. Bê, and the brilliant Henver Brunetta, uncovering a novel role of mitochondrial IF1 in the reverse mode of ATP synthase, enhancing bioenergetics in brown adipocytes I2MC-Toulouse INSPIRE Platform - IHU HealthAge biorxiv.org/content/10.110…

Congratulations to Y ROLLAND from Toulouse for his last publication about #ICOPE : "Implementing clinical operationalization of sarcopenia: the contribution of WHO ICOPE program." sciencedirect.com/science/articl… Bruno Vellas Isabelle ADER @RestoreInstitut Infinity Toulouse I2MC-Toulouse

The time to think and inquire are precious. Inquiring means to contemplate a problem without needing an immediate answer, to sit in the unknown long enough that different kinds of answers emerge. Important part of the process of discovery. nature.com/articles/d4158…

Excited to share our collaborative study with Alexander Bartelt Marcelo A. Mori Henver Brunetta, now online The EMBO Journal on a novel function of mitochondrial IF1 in thermogenesis. Grateful for the support from IHU HealthAge INSPIRE Platform - IHU HealthAge I2MC-Toulouse Mitochondria & Aging embopress.org/doi/full/10.10…

IHU Health Age Scientific Advisory Board

The powerhouse analogy has expired Like social organisms mitochondria differentiate and specialize to accomplish complex functions 🧵

Exited to share our latest review with Philipe de Souto Barreto on #Sarcopenia & the biological determinants of aging; Winner is Mitochondrial dysfunction! 🧬 We dive into the role of geroscience in age-related muscle decline.Bruno Vellas INSPIRE Platform - IHU HealthAge I2MC-Toulouse sciencedirect.com/science/articl…

If we look at thousands of proteins (i.e., signals) in the human blood, the protein most associated with chronic physical and mental illnesses is the **same protein** as the top marker for mitochondrial diseases: GDF15 When mitochondria cannot flux energy properly, the cell

Implementing the WHO ICOPE program in clinical practice: three years of lessons from monitoring 27,082 participants… pubmed.ncbi.nlm.nih.gov/39549299/

The impact on research ? : "Mitochondrial segmentation and function prediction in live-cell images with deep learning" doi.org/10.1038/s41467… Bruno Vellas Isabelle ADER @RestoreInstitut Infinity Toulouse I2MC-Toulouse Martinez Laurent