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Excited to share a new preprint! (1)🔬The nucleolus is the most prominent nuclear condensate, with a fascinating multilayered liquid-like structure, and is the site of ribosome biogenesis. But how does this multiphase architecture form and function? biorxiv.org/content/10.110…

Interested in #rRNA #modifications? Pls take a look at our latest preprint, a work beautifully led by Ivan Milenkovic, examining rRNA mod #heterogeneity across tissues, cell types, developmental stages and disease. PS. they also show promise as #biomarkers! biorxiv.org/content/10.110…

The The RNA Society congratulates our amazing and brilliant #RNA colleagues Dr. Victor Ambros UMass Chan Medical School and Dr. Gary Ruvkun Harvard Medical School on being awarded the 2024 The Nobel Prize in Physiology or Medicine “for the discovery of #microRNA and its role in post-transcriptional gene

Very happy to share our SeqTagger work, led by the super-team of Gregor Diensthuber and #Leszek, to barcode and demultiplex #directRNA Oxford Nanopore data - also works with #RNA004 data! Code available in GitHub, feedback very welcome! :-) biorxiv.org/content/10.110…

Delighted to co-supervise 2 advertised @BBSRCWhiteRose PhD projects 1- lncRNA function in human papillomavirus life cycle (led by Andrew Macdonald) 2-Building orthogonal ribosome control for engineering biology (led by Eszter Csibra ) findaphd.com/phds/?Keywords…

I have an open 12-month #postdoc position (net salary approx 2100€/month) in my lab to work on a fully funded collaborative project on #snoRNA #RNA in #cancer. Both #bioinfo #compbio and #molbio profiles can apply! Deadline: 16/12 12.00 Apply here: lavoraconnoi.unitn.it/en/research-co…

Open #postdoc position in the lab! please RT

Amazing ribosomes and... incredible cytokines 😯👇 P-stalk ribosomes act as master regulators of cytokine-mediated processes: Cell cell.com/cell/fulltext/…

Online Now: Structural dynamics of human ribosomes in situ reconstructed by exhaustive high-resolution template matching dlvr.it/TGXlng

Online Now: Epitranscriptomic rRNA fingerprinting reveals tissue-of-origin and tumor-specific signatures dlvr.it/TGj9sL

Discover how unique ribosome fingerprints could revolutionize early cancer detection with non-invasive, portable scanners able to detect cancer with near-perfect accuracy. #RNA #CancerResearch #EarlyDetection #Ribosome #Genomics #NanoporeSequencing science-tldr.com/news/ribosome-…

A role for the kinetochore protein, NUF2, in ribosome biogenesis | Molecular Biology of the Cell molbiolcell.org/doi/abs/10.109… New paper from ty brown in the Baserga Lab! Fabulous collaboration with Kabeche Lab ! Yale MB&B Yale Cancer Center.

Read our latest issue here: cell.com/molecular-cell…

Translation UK 2025 is coming 😊

Charting the epitranscriptomic landscape across RNA biotypes using native RNA nanopore sequencing dlvr.it/THRzDd

We are thrilled to share our exciting collaboration with ⁦Green Lab⁩ , showing that RIOK3 specifically recognizes ubiquitylated human 40S ribosomes and mediates their degradation under amino acid starvation. We even observed the melting 40S! cell.com/molecular-cell…

DM me if interested! We have opportunities at all levels.

A PhD position is available to decipher the modus operandi of ribosome-inactivating proteins at Maria Curie-Skłodowska University, Poland 🔬 Cryo-EM, biochemistry, structural biology 📅 Apply by July 31, 2024 🔗 euraxess.ec.europa.eu/jobs/344096 #CryoEM #Ribosome translacore.eu/article/job-of…

RNase L cleaves most tRNAs in the anticodon loops into various tRNA-derived RNAs (tDRs) including 5'-tDRAla that shows a translation inhibitory effect. Some tRNAs are also cleaved in variable loops. bit.ly/3YTwlNq