*Preprint alert* Together with The Kennedy Lab, Josh Jones developed the most sensitive LC-MS/MS method to date for quantifying RNA mods. Tyler Smith & Monika Franco reveal that some of the mods he detects in mRNAs (m1G, m2G, m5U) impact translation. biorxiv.org/content/10.110…

The promises and pitfalls of specialized ribosomes dlvr.it/SSScdW

Last preprint announcement for a few weeks😀. This fun collab with Aaron T. Frank & Dr. Bijoyita Roy investigated translation of mRNAs containing N1-methylpseudoU/pseudoU. Amino acid substitution is tuned UP and DOWN by mods depending on their sequence context! biorxiv.org/content/10.110…

Today our paper in partnership with ⁦⁦Puglisi Labs⁩ is published 👇🏽 Great effort from ⁦Chris Lapointe⁩ 👏🎉 Very proud of this 💪! nature.com/articles/s4158…

POSTDOC OPENING: We are recruiting a postdoc to develop live-cell #SingleMolecule #SuperResolution methods! I'd love to talk to great candidates with experience in #Biophysics, #Optics, #Microscopy, #ImageAnalysis, OR #Microbiology. More details: dropbox.com/s/u69813v5ywu2…

We seek new faculty who will develop a distinghished research program, excel in teaching and mentoring, promote an inclusive scholarly environment, and commit to building a diverse intellectual community. Please apply and/or distribute!

Profs. Chuan He and Tao Pan did it again! 🥳Their stunning work quantitatively maps PseudoU and reveals codon recoding at PseudoU sites in **endogenous mRNAs**! Their work and our related News&Views article are available at: nature.com/articles/s4158… & nature.com/articles/s4158…

We're hiring! Multiple fully-funded postdoc positions are available in my lab in the NIH Intramural Program in Bethesda. We're looking for people excited to take advantage of the great scientific resources and RNA community on campus. Please DM for details and RT!

If you missed our preprint, it's now out in PNASNews! Using a machine learning algorithm, we analyze temperature-dependent smFRET data to uncover the role of conformational entropy in regulating the functions of biomolecular machines such as the ribosome! pnas.org/doi/10.1073/pn…

Congratulations to Michigan Chemistry’s very own Alex Franklin for being honored with the 2023 Kay Beattie Outstanding Individual Award! It is truly well-deserved recognition!!

It's been a week folks! The project that defined my PhD has been published today in nature: nature.com/articles/s4158…. Congrats to everyone involved in this work and a huge thank you to Hashim and Dan for their mentorship!! Also, my name is not a typo ! 1/2

My lab has two open positions for Ph.D. or M.Sc. students studying RNA modifications UManitoba Science ! For details, visit our website: kothegroup.ca/news/ @RNACanada RiboClub @ARRTI CSMB The RNA Society

We are so excited for the Molecules of Life exhibit that is now up at the Museum of Natural History! Come check out Liz's amazing work bringing Biophysics 421 student's animations and 3D printed molecules to the public! University of Michigan Museum of Natural History Michigan Biophysics

We are excited to announce the 2023 Rustbelt RNA Meeting (#RRM2023) in East Lansing, MI. The meeting will be held Oct. 27-28. Registration will open next week. rustbeltrna.org

Excited to share the fantastic method developed by Josh Jones and Kaley Simcox to directly sequence total tRNAs from yeast by LC-MS/MS. rnajournal.cshlp.org/content/29/8/1…

Thank you to Michigan for supporting our work! Big shout to to all of the *fabulous* trainees and staff that keep our program rolling along.

Fantastic start to day 2 of #SRCKC24 with a Tandem Talk (where PI & trainee take the stage together!) from Koutmou Lab and Minli from University of Michigan! #RNA #research

Calling all RNA loving bakers and artists! The 2024 RNA-themed Baking and Art Competition for RNA Day (Aug 1) is underway. Original RNA-themed confections and visual art celebrating all aspects of RNA or the RNA Society are welcome. Winning submissions will receive $100 and be