New content online: Electroactive membrane fusion-liposome for increased electron transfer to enhance radiodynamic therapy dlvr.it/St8dYD

Big thanks to Penn Engineering for featuring our recent work in Nature Nanotechnology led by Mike Mitchell postdoc Xuexiang Han in collaboration with The Drew Weissman Lab on new adjuvant lipid-like materials that augment the immunogenicity of COVID-19 mRNA LNP vaccines! blog.seas.upenn.edu/an-improved-de…

Our latest Perspective by Sharon Gerecht & colleagues discusses how microenvironmental cues from the extracellular matrix guide macrophage-endothelium interactions, and how biomaterials can be used to replicate these interactions: nature.com/articles/s4157… Ya Guan @Gerechtlab

When EVs don't stand for electric vehicles.... Extracellular vesicles are the "FedEx for your cells" as laid out in this new feature nature by Alison Abbott with many clinical implications nature.com/articles/d4158…

🪇Read in #JEV🪇These authors propose a membrane-specific isolation and two-step cascade amplification strategy to isolate and detect EV proteins with 10 ul plasma within 4 hours, which showed good diagnostic results in early diagnosis of breast cancer. 👉bit.ly/3Z4OiXU

We are organizing the first Nature Conferences in India, and bringing together international researchers covering different nanoparticles applications such as theranostics, bio-imaging, drug delivery, nanovaccines, and immunotherapy. #NanomaterialsManipal2024 go.nature.com/400yp5p

The position probability distributions of eight stationary states of hydrogen atom: They show the likelihood of finding the electron in a given region of space around the nucleus, depending on the quantum numbers n, l, and m. The wave functions are solutions to the Schrödinger

Cool approach to use gold NP loaded hydrogel to augment muscle rehab with electrical stimulation. I had the pleasure of writing expert opinion about it. Impressive work. Hydrogel implant rehabilitates muscles through electrical stimulation nature.com/articles/d4158…

BMCPharmacolToxicol welcomes submissions to a article Collection on 'Developments in Selective Drug Deliveries'. Guest Edited by Koushik Debnath and Vijayabhaskarreddy Junnuthula. To learn more, visit: biomedcentral.com/collections/DSD

VERY excited to welcome this paper out in Nature Biomedical Engineering where we introduce the GEMINI platform for engineering multifunctional extracellular vesicles as versatile, programmable, biological delivery vehicles nature.com/articles/s4155…

Delighted to introduce 'matrimeres', a novel class of cell-secreted non-vesicular nanoparticles assembled by extracellular matrix and DNA molecules. Matrimeres can be synthesized without cells, and hence are versatile and programmable. ift.tt/9IhmQTd

The study was possible with funding from AmericanHeart and @nih_nhlbi. Work done collaboratively with MGH Cardiovascular Research Center @TGen and Vanderbilt Health. First study to show mapping of EV transcripts to single nuclear RNAseq atlas. ahajournals.org/eprint/KAIQX6T…

Way to Melbourne #ISEV2024 Ravindran Lab #UIC #koushikchem

Nanomedicines can enhance the properties of immunologic agents for preventing and treating respiratory infections. This article covers engineering strategies for nanomedicines across various administration routes: bit.ly/3Fje5pK

A chemical toolbox for surface engineering of extracellular vesicles bit.ly/3YIZevl

Excited to share this new work exploring EV heterogeneity! Honored to have had a small part in this important work. Extracellular vesicle heterogeneity through the lens of multiomics: Cell Reports Medicine cell.com/cell-reports-m…

Atoms captured at unprecedented resolution. This is praseodymium orthoscandate (PrScO₃), magnified 100 million times. Each dot is an atom in a crystal lattice. The slight blur? Atoms vibrate from thermal motion—this image shows their natural state. Achieved via ptychography

Excited to share our new paper! We engineered innate immune-cloaked MSCs in microgels to resolve persistent lung fibrosis. Single-cell RNA-seq revealed a key macrophage population, suggesting reparative macrophage therapies & “living pharmacy” strategies. doi.org/10.1002/adma.2…

Excited to share our review on Induced Proximity-based therapeutic modalities now out in Nature Reviews Drug Discovery! nature.com/articles/s4157…

Congratulations to Yonger Xue & Xucheng Hou for leading the wonderful work on peptibody mRNA! Thanks Miriam Merad, MD, PhD for the huge support! Thanks Rong Li Nature Biotechnology and reviewers for the amazing review process! Thanks NIH Icahn School of Medicine at Mount Sinai!