💢What is glomerular paralysis❓ ⚡️TMA with severe vascular lesion 👉Distended glomeruli with severe congestion 🔆Classically in TMA with thrombus in Afferent art or terminal interlobular art upstream of involved glomerulus Pic-Silva's Pathology #NephroNotes #NephPearls #FOAMed

📛Chronic Hypokalemia ⚡Induce renal vasoconstriction/ ischemia ⚡Local NH3 production👉Comp activation ⚡Intracellular acidosis👉 Cell proliferation👉Cyst ⚡⬇️Aquaporin2 expression👉⬇️CT responsiveness to AVP ⚡PCT vacuolization Ref-KI Reports #NephroNotes #Nephpearls #FOAMed

🌸25OH-Vitamin D3 1αhydroxylase in Kidney: Exact site of expression 👉Earlier thought to be exclusively PCT ⚡IHC reveal expression in DCT/CD, papillary epithelia, TALOH, Bowman cap‼ ⚡🚫 glomeruli/ vessels‼ Ref-jasn.asnjournals.org/content/10/12/… #Nephpearls #NephroNotes #FOAMed #Medtwitter

🌸Resistant Hypertension ⚡ABPM is must ⚡ABPM classifies it further 👉White coat RH (40%‼) 👉True RH 👉Sustained controlled RH 👉Masked RH ⚡Add MRA ⚡Role of Non-steroidal MRA emerging (Finerenone) #Nephpearls #NephroNotes #FOAMed #MedTwitter Ref-HTN Reasearch 2013

🌟Cadmium & Kidneys ⚡️Preferentially concentrated in PCT as Cd-metallothionein complex (Biological t1/2~ 10yrs‼️) 👉PT dysfunction, Renal stones, Anemia, CIN ⬆️Urinary β2M ⬆️Urinary Cd>7µgm/gm Cr ⚡️Prevention only effective T/t‼️ #NephroNotes #NephPearls #FOAMed #MedTwitter

🔥Hypercalcemic Nephropathy ⚡️Transient reversible renal vasoconstriction ⚡️Tubular cell necrosis ⚡️Intratubular obstruction 🔥Most distinctive histo feature: Nephrocalcinosis 👉Deposition begin in medullary tubules 👉Von Kossa staining #NephroNotes #FOAMed #MedEd #NephPearls

💥There is more to #Finerenone & Figure of Five‼️ 🔥Finerenone Pentad 🔆Selection Pentad 👉Five points of inclusion 👉Five points of exclusion 👉Five points regardless 🔆Monitoring Pentad 🔆Outcome Pentad #NephPearls #FOAMed #MedEd #MedTwitter #diabetes #kidney

Rationale and Design of the International Prospective Study of #CKD of #UncertainEtiology in #Agricultural Communities #VisualAbstract by 💙🦋 Jade Teakell kireports.org/article/S2468-…

Kidney stone disease: risk factors, pathophysiology and management nature.com/articles/s4158…

🌍 Showcase your work on a global stage. Presenting your abstract at the #ISNWCN isn’t just about sharing results it’s about shaping the future of kidney care. 🏆 Past awardees have gained international recognition, and now your work can win Best Abstract Awards. 📅 Abstract

KDIGO is pleased to share the publication of the APOL1 Kidney Disease Controversies Conference Report in Kidney International. Co-chaired by Akinlolu Ojo, MD (United States) and Ifeoma Ulasi, MD (Nigeria), the Accra, Ghana conference brought together scientists, clinicians, and

📖 This weekend, don't miss our KIReports #ISNFridaySelection: Anti-Rituximab Antibodies Occurrence and Clinical Outcomes in Patients with Primary Membranous Nephropathy kireports.org/article/S2468-…, and commentary: Anti-rituximab Antibodies in Primary Membranous Nephropathy: Time

How I Treat: Genetic Testing in Atypical Hemolytic Uremic Syndrome buff.ly/36xuPLq

🩺 The i3C initiative is developing a CKDu toolkit to support healthcare providers in international or local research. Help shape it by completing our short survey by Sept 3, 2025 ➡️ surveymonkey.com/r/ISN_i3C_CKDu… #CKDu #KidneyHealth #Research

In practice, I often see Hydralazine being prescribed as a first-line antihypertensive agent 🫣 ⚠️ Side effects: Fluid retention, tachycardia, ANCA Vasculitis 🔥 📌 These potent vasodilators are not first line and when used in the treatment of resistant #hypertension, they may

💥Transplant Drug Update #ISOT_eduConnect 🔥IL-2 Blockade: The Simplicity and Efficacy of Basiliximab 📅 16-08-2025 🕰️ 06:30 PM IST Join tomorrow! 🔗 us06web.zoom.us/j/81179699949?…

Now online in NDT Cost-effectiveness of protein restricted diets in advanced CKD 🧐In pts adherent to diet prescription, low-protein diets delay the start of dialysis, improve survival, and save money ▶️academic.oup.com/ndt/article-ab…

A #qualitative study in #ASNCJASN investigated patient perspectives on frailty and its management. Read more: kidney.pub/CJASN0796

Exact reason why diuretics cause hyperuricemia

Where is 1-α hydroxylase located in Kidney? Not PCT alone!