Kelvin William Pond
@kelvin_pond
Biologist studying epithelial self-organization using human organoids
ID: 1497215887534800896
http://www.pondlab.org 25-02-2022 14:24:51
70 Tweet
135 Followers
104 Following
My first preprint from the Chubb Lab UCL Laboratory for Molecular Cell Biology: Signalling centre vortices coordinate collective behaviour in social amoebae biorxiv.org/content/10.110…
Now in print! The molecular architecture of cell cycle arrest embopress.org/doi/10.15252/m… Spearheaded by now-independent Stallaert Lab Like many great studies, this one generated as many questions as answers. For example...
Our study done in Matsuda lab Michiyuki Matsuda is out in Developmental Cell ! We found that the sustained HGF-ERK signaling based on a physically regulated positive feedback loop specifies the leader cells during collective cell migration.
Our latest preprint💥 Tissue deformation is critical for organ generation, but how do complex organs consisting of multiple compartments and cell types achieve this? A fantastic interdisciplinary collab with M. Lisa Manning biorxiv.org/content/10.110… short🧵👇
Are colorectal cancer stem cells mechanically distinct from the rest of the tumor? Sefora Conti addressed this question using patient-derived colorectal cancer organoids. The answer is yes and you can read it in our new preprint (LGR5+ CSCs labelled red) biorxiv.org/content/10.110…
Just out before the holidays!🎄 Happy to share the result of a fun collaboration with Alpha Yap, out today in Nature Reviews Molecular Cell Biology. We hope you find it useful and informative: ➡️ rdcu.be/dtvWC #adherensjunctions #mechanobiology #morphogenesis #embryomechanics